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DPP4 抗体

This anti-DPP4 antibody is a 兔 多克隆 antibody detecting DPP4 in WB, IHC, IF 和 ELISA. Suitable for 人, 大鼠 和 Hamster.
产品编号 ABIN7113503
发货至: 中国

Quick Overview for DPP4 抗体 (ABIN7113503)

抗原

See all DPP4 抗体
DPP4 (Dipeptidyl-Peptidase 4 (DPP4))

适用

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人, 大鼠, Hamster

宿主

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  • 1

克隆类型

  • 90
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  • 1
多克隆

标记

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This DPP4 antibody is un-conjugated

应用范围

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Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF), ELISA
  • 纯化方法

    Immunogen affinity purified

    纯度

    ≥95 % as determined by SDS-PAGE

    免疫原

    dipeptidyl-peptidase 4

    亚型

    IgG
  • 应用备注

    WB: 1:500-1:1000, IHC: 1:20-1:200, IF: 1:10-1:100

    限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

    PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    -20°C for 12 months (Avoid repeated freeze / thaw cycles.)

    有效期

    12 months
  • 抗原

    DPP4 (Dipeptidyl-Peptidase 4 (DPP4))

    别名

    DPP4

    背景

    Synonyms:ADABP, ADCP 2, ADCP2, CD26, dipeptidyl peptidase 4, Dipeptidyl peptidase IV, DPP IV, DPP4, DPPIV, T cell activation antigen CD26, TP103 Background:Cell surface glycoprotein receptor involved in the costimulatory signal essential for T-cell receptor(TCR)-mediated T-cell activation. Acts as a positive regulator of T-cell coactivation, by binding at least ADA, CAV1, IGF2R, and PTPRC. Its binding to CAV1 and CARD11 induces T-cell proliferation and NF-kappa-B activation in a T-cell receptor/CD3-dependent manner. Its interaction with ADA also regulates lymphocyte-epithelial cell adhesion. In association with FAP is involved in the pericellular proteolysis of the extracellular matrix(ECM), the migration and invasion of endothelial cells into the ECM. May be involved in the promotion of lymphatic endothelial cells adhesion, migration and tube formation. When overexpressed, enhanced cell proliferation, a process inhibited by GPC3. Acts also as a serine exopeptidase with a dipeptidyl peptidase activity that regulates various physiological processes by cleaving peptides in the circulation, including many chemokines, mitogenic growth factors, neuropeptides and peptide hormones. Removes N-terminal dipeptides sequentially from polypeptides having unsubstituted N-termini provided that the penultimate residue is proline.

    分子量

    55-60 kDa

    基因ID

    1803

    UniProt

    P27487

    途径

    Peptide Hormone Metabolism, Regulation of Leukocyte Mediated Immunity
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