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Desmoglein 1 抗体

This anti-Desmoglein 1 antibody is a 兔 多克隆 antibody detecting Desmoglein 1 in WB, IHC, IF 和 ELISA. Suitable for 人 和 大鼠.
产品编号 ABIN7113447
发货至: 中国

Quick Overview for Desmoglein 1 抗体 (ABIN7113447)

抗原

See all Desmoglein 1 (DSG1) 抗体
Desmoglein 1 (DSG1)

适用

  • 107
  • 24
  • 11
  • 4
  • 3
  • 2
  • 2
  • 2
  • 1
  • 1
  • 1
人, 大鼠

宿主

  • 62
  • 46
  • 1

克隆类型

  • 56
  • 53
多克隆

标记

  • 47
  • 11
  • 6
  • 4
  • 3
  • 3
  • 3
  • 3
  • 3
  • 3
  • 3
  • 3
  • 3
  • 3
  • 3
  • 3
  • 2
  • 1
  • 1
  • 1
This Desmoglein 1 antibody is un-conjugated

应用范围

  • 56
  • 47
  • 31
  • 23
  • 20
  • 13
  • 10
  • 7
  • 5
  • 3
  • 2
  • 2
  • 1
  • 1
  • 1
Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF), ELISA
  • 纯化方法

    Immunogen affinity purified

    纯度

    ≥95 % as determined by SDS-PAGE

    免疫原

    Desmoglein-1

    亚型

    IgG
  • 应用备注

    WB: 1:500-1:2000, IHC: 1:50-1:200, IF: 1:50-1:200

    限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

    PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    -20°C for 12 months (Avoid repeated freeze / thaw cycles.)

    有效期

    12 months
  • 抗原

    Desmoglein 1 (DSG1)

    别名

    DSG1

    背景

    Synonyms:DSG1, CDHF4, DG1, DSG Background:This gene encodes a member of the desmoglein protein subfamily. Desmogleins, along with desmocollins, are cadherin-like transmembrane glycoproteins that are major components of the desmosome. Desmosomes are cell-cell junctions that help resist shearing forces and are found in high concentrations in cells subject to mechanical stress. This gene is found in a cluster with other desmoglein family members on chromosome 18. The encoded protein has been identified as a target of auto-antibodies in the autoimmune skin blistering disease pemphigus foliaceus. Disruption of this gene has also been associated with the skin diseases palmoplantar keratoderma and erythroderma.

    分子量

    150 kDa

    UniProt

    Q02413

    途径

    Cell-Cell Junction Organization
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