Desmoglein 1 抗体
Quick Overview for Desmoglein 1 抗体 (ABIN7113447)
抗原
See all Desmoglein 1 (DSG1) 抗体适用
宿主
克隆类型
标记
应用范围
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原理
- DSG1 antibody
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纯化方法
- Immunogen affinity purified
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纯度
- ≥95 % as determined by SDS-PAGE
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免疫原
- Desmoglein-1
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亚型
- IgG
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应用备注
- WB: 1:500-1:2000, IHC: 1:50-1:200, IF: 1:50-1:200
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid repeated freeze / thaw cycles.
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储存条件
- -20 °C
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储存方法
- -20°C for 12 months
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有效期
- 12 months
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- Desmoglein 1 (DSG1)
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别名
- DSG1
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背景
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Synonyms: Desmoglein-1|Cadherin family member 4|Desmosomal glycoprotein 1 (DG1, DGI)|Pemphigus foliaceus antigen|DSG1|CDHF4
Background: This gene encodes a member of the desmoglein protein subfamily. Desmogleins, along with desmocollins, are cadherin-like transmembrane glycoproteins that are major components of the desmosome. Desmosomes are cell-cell junctions that help resist shearing forces and are found in high concentrations in cells subject to mechanical stress. This gene is found in a cluster with other desmoglein family members on chromosome 18. The encoded protein has been identified as a target of auto-antibodies in the autoimmune skin blistering disease pemphigus foliaceus. Disruption of this gene has also been associated with the skin diseases palmoplantar keratoderma and erythroderma.
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分子量
- 150 kDa
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基因ID
- 1828
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UniProt
- Q02413
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途径
- Cell-Cell Junction Organization
抗原
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