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DCUN1D1 抗体

DCUN1D1 适用: 人, 小鼠, 大鼠 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN7113384
发货至: 中国
  • 抗原 See all DCUN1D1 抗体
    DCUN1D1 (Defective in Cullin Neddylation 1, Domain Containing 1 (DCUN1D1))
    适用
    • 35
    • 5
    • 4
    • 3
    • 3
    • 3
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    人, 小鼠, 大鼠
    宿主
    • 29
    • 4
    • 2
    克隆类型
    • 32
    • 3
    多克隆
    标记
    • 16
    • 3
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This DCUN1D1 antibody is un-conjugated
    应用范围
    • 31
    • 14
    • 13
    • 13
    • 5
    • 5
    • 3
    • 2
    • 1
    Western Blotting (WB), ELISA, Immunohistochemistry (IHC)
    纯化方法
    Immunogen affinity purified
    纯度
    ≥95 % as determined by SDS-PAGE
    免疫原
    DCN1, defective in cullin neddylation 1, domain containing 1(S. cerevisiae)
    亚型
    IgG
    Top Product
    Discover our top product DCUN1D1 Primary Antibody
  • 应用备注
    WB: 1:500-1:2000, IHC: 1:20-1:200
    限制
    仅限研究用
  • 状态
    Liquid
    缓冲液
    PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    -20 °C
    储存方法
    -20°C for 12 months (Avoid repeated freeze / thaw cycles.)
    有效期
    12 months
  • 抗原
    DCUN1D1 (Defective in Cullin Neddylation 1, Domain Containing 1 (DCUN1D1))
    别名
    DCUN1D1 (DCUN1D1 产品)
    别名
    fd19a01 antibody, zgc:66414 antibody, wu:fd19a01 antibody, dcun1l1 antibody, rp42 antibody, sccro antibody, scro antibody, tes3 antibody, DCNL1 antibody, DCUN1L1 antibody, RP42 antibody, SCCRO antibody, SCRO antibody, Tes3 antibody, Rp42 antibody, pTes3 antibody, DCN1, defective in cullin neddylation 1, domain containing 1 (S. cerevisiae) antibody, DCN1-like protein 1 antibody, DCN1, defective in cullin neddylation 1, domain containing 1 L homeolog antibody, defective in cullin neddylation 1 domain containing 1 antibody, dcun1d1 antibody, dcnl1 antibody, dcun1d1.L antibody, DCUN1D1 antibody, Dcun1d1 antibody
    背景
    Synonyms:DCUN1L1, RP42, SCCRO Background:Part of an E3 ubiquitin ligase complex for neddylation. Promotes neddylation of cullin components of E3 cullin-RING ubiquitin ligase complexes. Acts by binding to cullin-RBX1 complexes in the cytoplasm and promoting their nuclear translocation, enhancing recruitment of E2-NEDD8(UBE2M-NEDD8) thioester to the complex, and optimizing the orientation of proteins in the complex to allow efficient transfer of NEDD8 from the E2 to the cullin substrates(PubMed:25349211). Involved in the release of inhibitory effets of CAND1 on cullin-RING ligase E3 complex assembly and activity. Acts also as an oncogene facilitating malignant transformation and carcinogenic progression(By similarity).
    分子量
    28 kDa
    基因ID
    54165
    UniProt
    Q96GG9
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