DCUN1D1 抗体
Quick Overview for DCUN1D1 抗体 (ABIN7113384)
抗原
See all DCUN1D1 抗体适用
宿主
克隆类型
标记
应用范围
-
-
原理
- DCUN1D1 antibody
-
纯化方法
- Immunogen affinity purified
-
纯度
- ≥95 % as determined by SDS-PAGE
-
免疫原
- DCN1, defective in cullin neddylation 1, domain containing 1
-
亚型
- IgG
-
-
anti-Defective in Cullin Neddylation 1, Domain Containing 1 (DCUN1D1) (AA 1-89) antibody
DCUN1D1 适用: 人 WB, ELISA, IF 宿主: 小鼠 Monoclonal 3D7 unconjugated
anti-Defective in Cullin Neddylation 1, Domain Containing 1 (DCUN1D1) (AA 1-89) antibodyDCUN1D1 适用: 人 WB, ELISA 宿主: 小鼠 Monoclonal 4B5 unconjugated
anti-Defective in Cullin Neddylation 1, Domain Containing 1 (DCUN1D1) (AA 1-259) antibodyDCUN1D1 适用: 人 WB, IP 宿主: 兔 Polyclonal unconjugated
anti-Defective in Cullin Neddylation 1, Domain Containing 1 (DCUN1D1) (AA 1-89) antibodyDCUN1D1 适用: 人 WB, ELISA 宿主: 小鼠 Polyclonal unconjugated
anti-Defective in Cullin Neddylation 1, Domain Containing 1 (DCUN1D1) (AA 31-80) antibodyDCUN1D1 适用: 人, 小鼠, 大鼠, 犬, Cow, 马, 兔, 豚鼠, Bat, 小鸡, 猴, 非洲爪蟾, Pig WB, IHC, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Defective in Cullin Neddylation 1, Domain Containing 1 (DCUN1D1) antibodyDCUN1D1 适用: 人, 小鼠, 大鼠, 犬 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-Defective in Cullin Neddylation 1, Domain Containing 1 (DCUN1D1) (N-Term) antibodyDCUN1D1 适用: 人, 小鼠, 大鼠, 犬, Cow, 马, 兔, 豚鼠 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-Defective in Cullin Neddylation 1, Domain Containing 1 (DCUN1D1) (AA 1-259) antibodyDCUN1D1 适用: 人 ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Defective in Cullin Neddylation 1, Domain Containing 1 (DCUN1D1) (AA 15-70) antibodyDCUN1D1 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
anti-Defective in Cullin Neddylation 1, Domain Containing 1 (DCUN1D1) (C-Term) antibodyVerified DCUN1D1 适用: 人 WB, ELISA, IHC 宿主: 山羊 Polyclonal unconjugated
-
-
应用备注
- WB: 1:500-1:2000, IHC: 1:20-1:200
-
限制
- 仅限研究用
-
-
-
状态
- Liquid
-
缓冲液
- PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,
-
储存液
- Sodium azide
-
注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
-
注意事项
- Avoid repeated freeze / thaw cycles.
-
储存条件
- -20 °C
-
储存方法
- -20°C for 12 months
-
有效期
- 12 months
-
-
- DCUN1D1 (Defective in Cullin Neddylation 1, Domain Containing 1 (DCUN1D1))
-
别名
- DCUN1D1
-
背景
-
Synonyms: DCN1-like protein 1 (DCNL1)|DCUN1 domain-containing protein 1|Defective in cullin neddylation protein 1-like protein 1|Squamous cell carcinoma-related oncogene|DCUN1D1|DCN1|DCUN1L1|RP42|SCCRO
Background: Part of an E3 ubiquitin ligase complex for neddylation. Promotes neddylation of cullin components of E3 cullin-RING ubiquitin ligase complexes. Acts by binding to cullin-RBX1 complexes in the cytoplasm and promoting their nuclear translocation, enhancing recruitment of E2-NEDD8(UBE2M-NEDD8) thioester to the complex, and optimizing the orientation of proteins in the complex to allow efficient transfer of NEDD8 from the E2 to the cullin substrates(PubMed:25349211). Involved in the release of inhibitory effets of CAND1 on cullin-RING ligase E3 complex assembly and activity. Acts also as an oncogene facilitating malignant transformation and carcinogenic progression(By similarity).
-
分子量
- 28 kDa
-
基因ID
- 54165
-
UniProt
- Q96GG9
抗原
-
