DCUN1D1 抗体
Quick Overview for DCUN1D1 抗体 (ABIN7113384)
抗原
See all DCUN1D1 抗体适用
宿主
克隆类型
标记
应用范围
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纯化方法
- Immunogen affinity purified
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纯度
- ≥95 % as determined by SDS-PAGE
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免疫原
- DCN1, defective in cullin neddylation 1, domain containing 1(S. cerevisiae)
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亚型
- IgG
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anti-Defective in Cullin Neddylation 1, Domain Containing 1 (DCUN1D1) (AA 1-89) antibody
DCUN1D1 适用: 人 WB, ELISA, IF 宿主: 小鼠 Monoclonal 3D7 unconjugated
anti-Defective in Cullin Neddylation 1, Domain Containing 1 (DCUN1D1) (AA 1-89) antibodyDCUN1D1 适用: 人 WB, ELISA 宿主: 小鼠 Monoclonal 4B5 unconjugated
anti-Defective in Cullin Neddylation 1, Domain Containing 1 (DCUN1D1) (AA 1-259) antibodyDCUN1D1 适用: 人 WB, IP 宿主: 兔 Polyclonal unconjugated
anti-Defective in Cullin Neddylation 1, Domain Containing 1 (DCUN1D1) (AA 1-89) antibodyDCUN1D1 适用: 人 WB, ELISA 宿主: 小鼠 Polyclonal unconjugated
anti-Defective in Cullin Neddylation 1, Domain Containing 1 (DCUN1D1) (AA 31-80) antibodyDCUN1D1 适用: 人, 小鼠, 大鼠, 犬, Cow, 马, 兔, 豚鼠, Bat, 小鸡, 猴, 非洲爪蟾, Pig WB, IHC, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Defective in Cullin Neddylation 1, Domain Containing 1 (DCUN1D1) antibodyDCUN1D1 适用: 人, 小鼠, 大鼠, 犬 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-Defective in Cullin Neddylation 1, Domain Containing 1 (DCUN1D1) (N-Term) antibodyDCUN1D1 适用: 人, 小鼠, 大鼠, 犬, Cow, 马, 兔, 豚鼠 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-Defective in Cullin Neddylation 1, Domain Containing 1 (DCUN1D1) (AA 1-259) antibodyDCUN1D1 适用: 人 ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Defective in Cullin Neddylation 1, Domain Containing 1 (DCUN1D1) (C-Term) antibodyVerified DCUN1D1 适用: 人 WB, ELISA, IHC 宿主: 山羊 Polyclonal unconjugated
anti-Defective in Cullin Neddylation 1, Domain Containing 1 (DCUN1D1) (C-Term) antibody (Biotin)Verified DCUN1D1 适用: 人 WB, ELISA 宿主: 山羊 Polyclonal Biotin
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应用备注
- WB: 1:500-1:2000, IHC: 1:20-1:200
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- -20°C for 12 months (Avoid repeated freeze / thaw cycles.)
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有效期
- 12 months
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- DCUN1D1 (Defective in Cullin Neddylation 1, Domain Containing 1 (DCUN1D1))
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别名
- DCUN1D1
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背景
- Synonyms:DCUN1L1, RP42, SCCRO Background:Part of an E3 ubiquitin ligase complex for neddylation. Promotes neddylation of cullin components of E3 cullin-RING ubiquitin ligase complexes. Acts by binding to cullin-RBX1 complexes in the cytoplasm and promoting their nuclear translocation, enhancing recruitment of E2-NEDD8(UBE2M-NEDD8) thioester to the complex, and optimizing the orientation of proteins in the complex to allow efficient transfer of NEDD8 from the E2 to the cullin substrates(PubMed:25349211). Involved in the release of inhibitory effets of CAND1 on cullin-RING ligase E3 complex assembly and activity. Acts also as an oncogene facilitating malignant transformation and carcinogenic progression(By similarity).
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分子量
- 28 kDa
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基因ID
- 54165
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UniProt
- Q96GG9
抗原
-
