DOCK7 抗体
Quick Overview for DOCK7 抗体 (ABIN7113381)
抗原
See all DOCK7 抗体适用
宿主
克隆类型
标记
应用范围
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原理
- DOCK7 antibody
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纯化方法
- Immunogen affinity purified
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纯度
- ≥95 % as determined by SDS-PAGE
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免疫原
- dedicator of cytokinesis 7
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亚型
- IgG
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anti-Dedicator of Cytokinesis 7 (DOCK7) (AA 1440-1671) antibody
DOCK7 适用: 人 ELISA, WB, IF 宿主: 兔 Polyclonal unconjugated
anti-Dedicator of Cytokinesis 7 (DOCK7) (N-Term) antibodyDOCK7 适用: 人, 大鼠, 小鼠 ELISA, WB 宿主: 兔 Polyclonal unconjugated
anti-Dedicator of Cytokinesis 7 (DOCK7) (AA 1-624) antibodyDOCK7 适用: 人 WB 宿主: 小鼠 Polyclonal unconjugated
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应用备注
- WB: 1:200-1:1000, IP: 1:500-1:1000
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid repeated freeze / thaw cycles.
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储存条件
- -20 °C
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储存方法
- -20°C for 12 months
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有效期
- 12 months
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- DOCK7 (Dedicator of Cytokinesis 7 (DOCK7))
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别名
- DOCK7
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背景
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Synonyms: Dedicator of cytokinesis protein 7|DOCK7|KIAA1771
Background: Functions as a guanine nucleotide exchange factor(GEF), which activates Rac1 and Rac3 Rho small GTPases by exchanging bound GDP for free GTP. Does not have a GEF activity for CDC42. Required for STMN1 'Ser-15' phosphorylation during axon formation and consequently for neuronal polarization(PubMed:16982419). Has a role in pigmentation(By similarity). Involved in the regulation of cortical neurogenesis through the control of radial glial cells(RGCs) proliferation versus differentiation, negatively regulates the basal-to-apical interkinetic nuclear migration of RGCs by antagonizing the microtubule growth-promoting function of TACC3(By similarity).Multiple isoforms of DOCK 7 exist due to alternative splicing events. This DOCK 7 antibody can recognize all the isoforms.
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分子量
- 240 kDa
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基因ID
- 85440
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UniProt
- Q96N67
抗原
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