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DHX36 抗体

DHX36 适用: 人, 小鼠, 大鼠 WB, ELISA, IHC, IP 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN7113365
发货至: 中国
  • 抗原 See all DHX36 抗体
    DHX36 (DEAH (Asp-Glu-Ala-His) Box Polypeptide 36 (DHX36))
    适用
    人, 小鼠, 大鼠
    宿主
    • 44
    克隆类型
    • 44
    多克隆
    标记
    • 10
    • 5
    • 4
    • 4
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    This DHX36 antibody is un-conjugated
    应用范围
    • 33
    • 20
    • 13
    • 13
    • 4
    • 3
    • 2
    • 1
    • 1
    Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Immunoprecipitation (IP)
    纯化方法
    Immunogen affinity purified
    纯度
    ≥95 % as determined by SDS-PAGE
    免疫原
    DEAH(Asp-Glu-Ala-His) box polypeptide 36
    亚型
    IgG
    Top Product
    Discover our top product DHX36 Primary Antibody
  • 应用备注
    WB: 1:500-1:2000, IP: 1:200-1:1000, IHC: 1:20-1:200
    限制
    仅限研究用
  • 状态
    Liquid
    缓冲液
    PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    -20 °C
    储存方法
    -20°C for 12 months (Avoid repeated freeze / thaw cycles.)
    有效期
    12 months
  • 抗原
    DHX36 (DEAH (Asp-Glu-Ala-His) Box Polypeptide 36 (DHX36))
    别名
    DHX36 (DHX36 产品)
    别名
    DHX57 antibody, DDX36 antibody, G4R1 antibody, MLEL1 antibody, RHAU antibody, 2810407E23Rik antibody, AI452301 antibody, AU022184 antibody, Ddx36 antibody, mKIAA1488 antibody, DEAH-box helicase 36 antibody, ATP-dependent RNA helicase DHX36 antibody, DEAH (Asp-Glu-Ala-His) box polypeptide 36 antibody, Dhx36 antibody, DHX36 antibody, dhx36 antibody, LOC100456222 antibody, LOC100633205 antibody
    背景
    Synonyms:DDX36, KIAA1488, MLEL1, RHAU Background:Proposed to have a global role in regulating mRNA expression including transcriptional regulation and mRNA stability. Binds with high affinity to and resolves tetramolecular RNA and DNA quadruplex structures. Unwinds intramolecular quadruplexes derived from the ZIC1 and the MYC promoters. Binds to quadruplex structures in the promoters of YY1 and ALPL genes and regulates their expression. Binds to telomerase RNA template component(TERC) 5'-end(nucleotides 1-43) and unwinds an internal quadruplex formation in TERC 5'-end to promote P1 helix formation, the P1 helix acts as a template boundary ensuring accurate reverse transcription and is disrupted by quadruplex formation. May be involved in regulation of telomere length. Plays a role in degradation and deadenylation of mRNAs containing in their 3'-UTR the consensus ARE sequence element. May function in sex development and spermatogenesis. May play a role in ossification.
    分子量
    120 kDa
    基因ID
    170506
    UniProt
    Q9H2U1
    途径
    Toll-Like Receptors Cascades
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