DACH2 抗体
Quick Overview for DACH2 抗体 (ABIN7113311)
抗原
See all DACH2 抗体适用
宿主
克隆类型
标记
应用范围
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原理
- DACH2 antibody
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纯化方法
- Immunogen affinity purified
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纯度
- ≥95 % as determined by SDS-PAGE
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免疫原
- dachshund homolog 2(Drosophila)
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亚型
- IgG
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anti-Dachshund 2 (DACH2) antibody
DACH2 适用: 人, 小鼠 ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Dachshund 2 (DACH2) (AA 525-574) antibodyDACH2 适用: 人, 小鼠, 马, 兔, 大鼠, 斑马鱼, 小鸡, Pig, 非洲爪蟾 WB 宿主: 兔 Polyclonal unconjugated
anti-Dachshund 2 (DACH2) (Internal Region) antibodyVerified DACH2 适用: 小鼠 WB, ELISA 宿主: 山羊 Polyclonal unconjugated
anti-Dachshund 2 (DACH2) (C-Term) antibodyDACH2 适用: 人, 小鼠, 犬, 斑马鱼, 小鸡, 非洲爪蟾 WB 宿主: 兔 Polyclonal unconjugated
anti-Dachshund 2 (DACH2) (C-Term) antibodyDACH2 适用: 人, 小鼠, 马, 兔, 犬, 大鼠, Cow, 斑马鱼 WB 宿主: 兔 Polyclonal unconjugated
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应用备注
- WB: 1:500-1:2000
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid repeated freeze / thaw cycles.
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储存条件
- -20 °C
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储存方法
- -20°C for 12 months
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有效期
- 12 months
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- DACH2 (Dachshund 2 (DACH2))
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别名
- DACH2
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背景
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Synonyms: Dachshund homolog 2 (Dach2)|DACH2
Background: Transcription factor that is involved in regulation of organogenesis. Seems to be a regulator for SIX1 and SIX6. Seems to act as a corepressor of SIX6 in regulating proliferation by directly repressing cyclin-dependent kinase inhibitors, including the p27Kip1 promoter. Is recruited with SIX6 to the p27Kip1 promoter in embryonal retina. SIX6 corepression seems also to involve NCOR1, TBL1, HDAC1 and HDAC3. May be involved together with PAX3, SIX1, and EYA2 in regulation of myogenesis. In the developing somite, expression of DACH2 and PAX3 is regulated by the overlying ectoderm, and DACH2 and PAX3 positively regulate each other's expression(By similarity). Probably binds to DNA via its DACHbox-N domain.
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分子量
- 65 kDa
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基因ID
- 117154
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UniProt
- Q96NX9
抗原
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