Cyclin Y 抗体
Quick Overview for Cyclin Y 抗体 (ABIN7113157)
抗原
See all Cyclin Y (CCNY) 抗体适用
宿主
克隆类型
标记
应用范围
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原理
- CCNY antibody
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纯化方法
- Immunogen affinity purified
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纯度
- ≥95 % as determined by SDS-PAGE
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免疫原
- cyclin Y
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亚型
- IgG
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应用备注
- WB: 1:500-1:2000, IP: 1:500-1:1000, IF: 1:10-1:100
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid repeated freeze / thaw cycles.
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储存条件
- -20 °C
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储存方法
- -20°C for 12 months
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有效期
- 12 months
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- Cyclin Y (CCNY)
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别名
- CCNY
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背景
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Synonyms: Cyclin-Y (Cyc-Y)|Cyclin box protein 1|Cyclin fold protein 1|cyclin-X|CCNY|C10orf9|CBCP1|CFP1
Background: Positive regulatory subunit of the cyclin-dependent kinases CDK14/PFTK1 and CDK16. Acts as a cell-cycle regulator of Wnt signaling pathway during G2/M phase by recruiting CDK14/PFTK1 to the plasma membrane and promoting phosphorylation of LRP6, leading to the activation of the Wnt signaling pathway. Recruits CDK16 to the plasma membrane. Isoform 3 might play a role in the activation of MYC-mediated transcription.
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分子量
- 33-39 kDa
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基因ID
- 219771
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UniProt
- Q8ND76
抗原
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