CRYAB 抗体
Quick Overview for CRYAB 抗体 (ABIN7113086)
抗原
See all CRYAB 抗体适用
宿主
克隆类型
标记
应用范围
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原理
- CRYAB antibody
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纯化方法
- Immunogen affinity purified
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纯度
- ≥95 % as determined by SDS-PAGE
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免疫原
- crystallin, alpha B
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亚型
- IgG
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应用备注
- WB: 1:500-1:5000, IHC: 1:20-1:200, IP: 1:200-1:2000
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid repeated freeze / thaw cycles.
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储存条件
- -20 °C
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储存方法
- -20°C for 12 months
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有效期
- 12 months
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- CRYAB (Crystallin, alpha B (CRYAB))
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别名
- CRYAB
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背景
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Synonyms: Alpha-crystallin B chain|Alpha(B)-crystallin|Heat shock protein beta-5 (HspB5)|Renal carcinoma antigen NY-REN-27|Rosenthal fiber component|CRYAB|CRYA2|HSPB5
Background: Alpha B-crystallin, encoded by CRYAB gene, is multifunctional, serving as both a major structural protein in the lens and a small heat-shock protein in other tissues in mammals. Alpha B-crystallin may contribute to the transparency and refractive index of the lens. Single nucleotide polymorphisms(SNPs) in the promoter region of CRYAB gene have been associated with in multiple sclerosis. Mutations in the CRYAB gene cause distinct clinical phenotypes including isolated posterior polar cataract, myofibrillar myopathy, cardiomyopathy, or a multisystemic disorder combining all these features. Impairment of alpha-B crystallin dimerization may be relevant to the pathogenesis of these disorders.
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分子量
- 20 kDa
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UniProt
- P02511
抗原
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