Coxsackie Adenovirus Receptor 抗体
Quick Overview for Coxsackie Adenovirus Receptor 抗体 (ABIN7113073)
抗原
See all Coxsackie Adenovirus Receptor (CXADR) 抗体适用
宿主
克隆类型
标记
应用范围
-
-
纯化方法
- Immunogen affinity purified
-
纯度
- ≥95 % as determined by SDS-PAGE
-
免疫原
- coxsackie virus and adenovirus receptor
-
亚型
- IgG
-
-
-
-
应用备注
- WB: 1:500-1:2000, IHC: 1:20-1:200
-
限制
- 仅限研究用
-
-
-
状态
- Liquid
-
缓冲液
- PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,
-
储存液
- Sodium azide
-
注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
-
储存条件
- -20 °C
-
储存方法
- -20°C for 12 months (Avoid repeated freeze / thaw cycles.)
-
有效期
- 12 months
-
-
- Coxsackie Adenovirus Receptor (CXADR) (Coxsackie Virus and Adenovirus Receptor (CXADR))
-
别名
- CXADR
-
背景
- Synonyms:CAR Background:Component of the epithelial apical junction complex that may function as a homophilic cell adhesion molecule and is essential for tight junction integrity. Also involved in transepithelial migration of leukocytes through adhesive interactions with JAML a transmembrane protein of the plasma membrane of leukocytes. The interaction between both receptors also mediates the activation of gamma-delta T-cells, a subpopulation of T-cells residing in epithelia and involved in tissue homeostasis and repair. Upon epithelial CXADR-binding, JAML induces downstream cell signaling events in gamma-delta T-cells through PI3-kinase and MAP kinases. It results in proliferation and production of cytokines and growth factors by T-cells that in turn stimulate epithelial tissues repair. (Microbial infection) Acts as a receptor for adenovirus type C(PubMed:9733828, PubMed:10666333, PubMed:12297051, PubMed:10567268). Acts as a receptor for Coxsackievirus B1 to B6(PubMed:14978041, PubMed:10814575).
-
分子量
- 55 kDa
-
基因ID
- 1525
-
UniProt
- P78310
-
途径
- Cell-Cell Junction Organization
抗原
-