COPS4 抗体
Quick Overview for COPS4 抗体 (ABIN7113044)
抗原
See all COPS4 抗体适用
宿主
克隆类型
标记
应用范围
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纯化方法
- Immunogen affinity purified
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纯度
- ≥95 % as determined by SDS-PAGE
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免疫原
- COP9 constitutive photomorphogenic homolog subunit 4(Arabidopsis)
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亚型
- IgG
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anti-COP9 Signalosome Subunit 4 (COPS4) (AA 1-310) antibody
COPS4 适用: 人 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-COP9 Signalosome Subunit 4 (COPS4) (AA 53-102) antibodyCOPS4 适用: 人, 小鼠, 大鼠, Cow, 犬, 马, 兔, 豚鼠, Pig, Bat, Hamster, 猴 WB 宿主: 兔 Polyclonal unconjugated
anti-COP9 Signalosome Subunit 4 (COPS4) (AA 143-192) antibodyCOPS4 适用: 人, 小鼠, 大鼠, Cow, 犬, 马, 兔, 豚鼠, Pig, 斑马鱼, 小鸡, Bat, Hamster, 猴, 非洲爪蟾 WB 宿主: 兔 Polyclonal unconjugated
anti-COP9 Signalosome Subunit 4 (COPS4) (Middle Region) antibodyCOPS4 适用: 人, 小鼠, 大鼠, Cow, 犬, 马, 兔, 豚鼠, 斑马鱼 WB 宿主: 兔 Polyclonal unconjugated
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应用备注
- WB: 1:500-1:2000, IP: 1:200-1:1000, IHC: 1:20-1:200
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- -20°C for 12 months (Avoid repeated freeze / thaw cycles.)
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有效期
- 12 months
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- COPS4 (COP9 Signalosome Subunit 4 (COPS4))
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别名
- COPS4
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背景
- Synonyms:CSN4 Background:Component of the COP9 signalosome complex(CSN), a complex involved in various cellular and developmental processes. The CSN complex is an essential regulator of the ubiquitin(Ubl) conjugation pathway by mediating the deneddylation of the cullin subunits of SCF-type E3 ligase complexes, leading to decrease the Ubl ligase activity of SCF-type complexes such as SCF, CSA or DDB2. Also involved in the deneddylation of non-cullin subunits such as STON2. The complex is also involved in phosphorylation of p53/TP53, c-jun/JUN, IkappaBalpha/NFKBIA, ITPK1, IRF8/ICSBP and SNAPIN, possibly via its association with CK2 and PKD kinases. CSN-dependent phosphorylation of TP53 and JUN promotes and protects degradation by the Ubl system, respectively.
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分子量
- 40, 46 kDa
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基因ID
- 51138
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UniProt
- Q9BT78
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途径
- Cell Division Cycle
抗原
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