CPSF3 抗体
Quick Overview for CPSF3 抗体 (ABIN7112880)
抗原
See all CPSF3 抗体适用
宿主
克隆类型
标记
应用范围
-
-
原理
- CPSF3 antibody
-
纯化方法
- Immunogen affinity purified
-
纯度
- ≥95 % as determined by SDS-PAGE
-
免疫原
- cleavage and polyadenylation specific factor 3, 73kDa
-
亚型
- IgG
-
-
anti-Cleavage and Polyadenylation Specific Factor 3, 73kDa (CPSF3) (AA 585-684) antibody
CPSF3 适用: 人 WB, ELISA, IF 宿主: 小鼠 Monoclonal 6E6 unconjugated
anti-Cleavage and Polyadenylation Specific Factor 3, 73kDa (CPSF3) (AA 585-684) antibodyCPSF3 适用: 人 WB, ELISA 宿主: 小鼠 Monoclonal 1H8 unconjugated
anti-Cleavage and Polyadenylation Specific Factor 3, 73kDa (CPSF3) (AA 1-684) antibodyCPSF3 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
anti-Cleavage and Polyadenylation Specific Factor 3, 73kDa (CPSF3) antibodyCPSF3 适用: 人 WB 宿主: 兔 Monoclonal unconjugated
anti-Cleavage and Polyadenylation Specific Factor 3, 73kDa (CPSF3) (AA 1-684) antibodyCPSF3 适用: 人 WB, IF 宿主: 小鼠 Polyclonal unconjugated
anti-Cleavage and Polyadenylation Specific Factor 3, 73kDa (CPSF3) (C-Term) antibodyCPSF3 适用: 人, 大鼠, 兔, 猴 WB, IHC, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Cleavage and Polyadenylation Specific Factor 3, 73kDa (CPSF3) (C-Term) antibodyCPSF3 适用: 人 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-Cleavage and Polyadenylation Specific Factor 3, 73kDa (CPSF3) (AA 1-50) antibodyCPSF3 适用: 人, 小鼠, 大鼠, 犬, 兔, Cow, 马, 豚鼠, Pig WB, IHC, IF, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Cleavage and Polyadenylation Specific Factor 3, 73kDa (CPSF3) (AA 634-684) antibodyCPSF3 适用: 人, 小鼠 IHC, IF, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Cleavage and Polyadenylation Specific Factor 3, 73kDa (CPSF3) (AA 189-238) antibodyCPSF3 适用: 人, 小鼠, 大鼠, 犬, 兔, Cow, 马, 豚鼠, 斑马鱼, 猴, Pig, Bat, 小鸡, 非洲爪蟾 WB 宿主: 兔 Polyclonal unconjugated
-
-
应用备注
- WB: 1:500-1:2000
-
限制
- 仅限研究用
-
-
-
状态
- Liquid
-
缓冲液
- PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,
-
储存液
- Sodium azide
-
注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
-
注意事项
- Avoid repeated freeze / thaw cycles.
-
储存条件
- -20 °C
-
储存方法
- -20°C for 12 months
-
有效期
- 12 months
-
-
- CPSF3 (Cleavage and Polyadenylation Specific Factor 3, 73kDa (CPSF3))
-
别名
- CPSF3
-
背景
-
Synonyms: Cleavage and polyadenylation specificity factor subunit 3|Cleavage and polyadenylation specificity factor 73 kDa subunit (CPSF 73 kDa subunit)|mRNA 3'-end-processing endonuclease CPSF-73|CPSF3|CPSF73
Background: Component of the cleavage and polyadenylation specificity factor(CPSF) complex that play a key role in pre-mRNA 3'-end formation, recognizing the AAUAAA signal sequence and interacting with poly(A) polymerase and other factors to bring about cleavage and poly(A) addition. Has endonuclease activity, and functions as mRNA 3'-end-processing endonuclease. Also involved in the histone 3'-end pre-mRNA processing. U7 snRNP-dependent protein that induces both the 3'-endoribonucleolytic cleavage of histone pre-mRNAs and acts as a 5' to 3' exonuclease for degrading the subsequent downstream cleavage product(DCP) of mature histone mRNAs. Cleavage occurs after the 5'-ACCCA-3' sequence in the histone pre-mRNA leaving a 3'hydroxyl group on the upstream fragment containing the stem loop(SL) and 5' phosphate on the downstream cleavage product(DCP) starting with CU nucleotides. The U7-dependent 5' to 3' exonuclease activity is processive and degrades the DCP RNA substrate even after complete removal of the U7-binding site. Binds to the downstream cleavage product(DCP) of histone pre-mRNAs and the cleaved DCP RNA substrate in a U7 snRNP dependent manner.
-
分子量
- 77 kDa
-
基因ID
- 51692
-
UniProt
- Q9UKF6
抗原
-
