Claspin 抗体
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北京 101111
Quick Overview for Claspin 抗体 (ABIN7112861)
抗原
See all Claspin (CLSPN) 抗体适用
宿主
克隆类型
标记
应用范围
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原理
- CLSPN antibody
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纯化方法
- Immunogen affinity purified
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纯度
- ≥95 % as determined by SDS-PAGE
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免疫原
- claspin homolog(Xenopus laevis)
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亚型
- IgG
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anti-Claspin (CLSPN) (N-Term) antibody
CLSPN 适用: 人, 小鼠, 大鼠 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Claspin (CLSPN) (AA 650-750) antibodyCLSPN 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
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应用备注
- WB: 1:200-1:1000, IP: 1:500-1:2000, IF: 1:20-1:200
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid repeated freeze / thaw cycles.
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储存条件
- -20 °C
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储存方法
- -20°C for 12 months
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有效期
- 12 months
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- Claspin (CLSPN)
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别名
- CLSPN
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背景
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Synonyms: Claspin (hClaspin)|CLSPN
Background: Required for checkpoint mediated cell cycle arrest in response to inhibition of DNA replication or to DNA damage induced by both ionizing and UV irradiation. Adapter protein which binds to BRCA1 and the checkpoint kinase CHEK1 and facilitates the ATR-dependent phosphorylation of both proteins. Can also bind specifically to branched DNA structures and may associate with S-phase chromatin following formation of the pre-replication complex(pre-RC). This may indicate a role for this protein as a sensor which monitors the integrity of DNA replication forks.
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分子量
- 240 kDa
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基因ID
- 63967
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UniProt
- Q9HAW4
抗原
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