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CHI3L1 抗体 (AA 22-383)

This anti-CHI3L1 antibody is a 兔 多克隆 antibody detecting CHI3L1 in IHC 和 ELISA. Suitable for 人, 小鼠 和 大鼠.
产品编号 ABIN7112692
发货至: 中国

Quick Overview for CHI3L1 抗体 (AA 22-383) (ABIN7112692)

抗原

See all CHI3L1 抗体
CHI3L1 (Chitinase 3-Like 1 (Cartilage Glycoprotein-39) (CHI3L1))

适用

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人, 小鼠, 大鼠

宿主

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克隆类型

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  • 9
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多克隆

标记

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This CHI3L1 antibody is un-conjugated

应用范围

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Immunohistochemistry (IHC), ELISA
  • 抗原表位

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    AA 22-383

    原理

    CHI3L1 antibody

    纯化方法

    Immunogen affinity purified

    纯度

    ≥95 % as determined by SDS-PAGE

    免疫原

    Immunogen sequence: 22-383aa

    Immunogen: chitinase 3-like 1(cartilage glycoprotein-39)

    亚型

    IgG
  • 应用备注

    IHC: 1:50 - 1:200

    限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

    PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    注意事项

    Avoid repeated freeze / thaw cycles.

    储存条件

    -20 °C

    储存方法

    -20°C for 12 months

    有效期

    12 months
  • 抗原

    CHI3L1 (Chitinase 3-Like 1 (Cartilage Glycoprotein-39) (CHI3L1))

    别名

    CHI3L1

    背景

    Synonyms: Chitinase-3-like protein 1|39 kDa synovial protein|Cartilage glycoprotein 39 (CGP-39, GP-39, hCGP-39)|YKL-40|CHI3L1

    Background: Carbohydrate-binding lectin with a preference for chitin. Has no chitinase activity. May play a role in tissue remodeling and in the capacity of cells to respond to and cope with changes in their environment. Plays a role in T-helper cell type 2(Th2) inflammatory response and IL-13-induced inflammation, regulating allergen sensitization, inflammatory cell apoptosis, dendritic cell accumulation and M2 macrophage differentiation. Facilitates invasion of pathogenic enteric bacteria into colonic mucosa and lymphoid organs. Mediates activation of AKT1 signaling pathway and subsequent IL8 production in colonic epithelial cells. Regulates antibacterial responses in lung by contributing to macrophage bacterial killing, controlling bacterial dissemination and augmenting host tolerance. Also regulates hyperoxia-induced injury, inflammation and epithelial apoptosis in lung.

    分子量

    43 kDa

    基因ID

    1116

    UniProt

    P36222
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