CBY1/PGEA1 抗体
Quick Overview for CBY1/PGEA1 抗体 (ABIN7112690)
抗原
See all CBY1/PGEA1 (CBY1) 抗体适用
宿主
克隆类型
标记
应用范围
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原理
- CBY1 antibody
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纯化方法
- Immunogen affinity purified
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纯度
- ≥95 % as determined by SDS-PAGE
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免疫原
- chibby homolog 1(Drosophila)
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亚型
- IgG
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应用备注
- WB: 1:500-1:2000, IP: 1:500-1:1000, IHC: 1:50-1:200
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid repeated freeze / thaw cycles.
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储存条件
- -20 °C
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储存方法
- -20°C for 12 months
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有效期
- 12 months
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- CBY1/PGEA1 (CBY1) (Chibby Homolog 1 (CBY1))
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别名
- CBY1
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背景
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Synonyms: Protein chibby homolog 1|ARPP-binding protein|Cytosolic leucine-rich protein|PIGEA-14|PKD2 interactor, Golgi and endoplasmic reticulum-associated 1|CBY1|ARB1|C22orf2|CBY|PGEA1
Background: Inhibits the Wnt/Wingless pathway by binding to CTNNB1/beta-catenin and inhibiting beta-catenin-mediated transcriptional activation through competition with TCF/LEF transcription factors. Has also been shown to play a role in regulating the intracellular trafficking of polycystin-2/PKD2 and possibly of other intracellular proteins. Promotes adipocyte and cardiomyocyte differentiation.
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分子量
- 30-35 kDa
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基因ID
- 25776
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UniProt
- Q9Y3M2
抗原
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