CHMP2A 抗体
Quick Overview for CHMP2A 抗体 (ABIN7112645)
抗原
See all CHMP2A 抗体适用
宿主
克隆类型
标记
应用范围
-
-
原理
- CHMP2A antibody
-
纯化方法
- Immunogen affinity purified
-
纯度
- ≥95 % as determined by SDS-PAGE
-
免疫原
- chromatin modifying protein 2A
-
亚型
- IgG
-
-
anti-Charged Multivesicular Body Protein 2A (CHMP2A) (AA 1-222) antibody
CHMP2A 适用: 人 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Charged Multivesicular Body Protein 2A (CHMP2A) (Internal Region) antibodyCHMP2A 适用: 人, 大鼠, 小鼠 WB, IHC, ICC, IF 宿主: 兔 Polyclonal unconjugated
anti-Charged Multivesicular Body Protein 2A (CHMP2A) (AA 1-100) antibodyCHMP2A 适用: 大鼠 WB, ELISA, IF (cc), IF (p), IHC (p), ICC, IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-Charged Multivesicular Body Protein 2A (CHMP2A) (AA 1-222) antibodyCHMP2A 适用: 人 WB 宿主: 小鼠 Polyclonal unconjugated
anti-Charged Multivesicular Body Protein 2A (CHMP2A) antibody (FITC)CHMP2A 适用: 人 WB, ELISA, IHC, IHC (p) 宿主: 兔 Polyclonal FITC
anti-Charged Multivesicular Body Protein 2A (CHMP2A) antibody (HRP)CHMP2A 适用: 人 WB, ELISA, IHC, IHC (p) 宿主: 兔 Polyclonal HRP
anti-Charged Multivesicular Body Protein 2A (CHMP2A) antibody (Biotin)CHMP2A 适用: 人 WB, ELISA, IHC, IHC (p) 宿主: 兔 Polyclonal Biotin
anti-Charged Multivesicular Body Protein 2A (CHMP2A) (C-Term) antibodyCHMP2A 适用: 人, 大鼠, 小鼠, Cow, 豚鼠, 兔, Bat, 猴 WB 宿主: 兔 Polyclonal unconjugated
anti-Charged Multivesicular Body Protein 2A (CHMP2A) (N-Term) antibodyCHMP2A 适用: 人, 大鼠, 小鼠, Cow, 豚鼠, 兔, 犬, 斑马鱼, Bat, 猴, 小鸡, 非洲爪蟾 WB 宿主: 兔 Polyclonal unconjugated
-
-
应用备注
- WB: 1:500-1:2000
-
限制
- 仅限研究用
-
-
-
状态
- Liquid
-
缓冲液
- PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,
-
储存液
- Sodium azide
-
注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
-
注意事项
- Avoid repeated freeze / thaw cycles.
-
储存条件
- -20 °C
-
储存方法
- -20°C for 12 months
-
有效期
- 12 months
-
-
- CHMP2A (Charged Multivesicular Body Protein 2A (CHMP2A))
-
别名
- CHMP2A
-
背景
-
Synonyms: Charged multivesicular body protein 2a|Chromatin-modifying protein 2a (CHMP2a)|Putative breast adenocarcinoma marker BC-2|Vacuolar protein sorting-associated protein 2-1 (Vps2-1, hVps2-1)|CHMP2A|BC2|CHMP2
Background: Probable core component of the endosomal sorting required for transport complex III(ESCRT-III) which is involved in multivesicular bodies(MVBs) formation and sorting of endosomal cargo proteins into MVBs. MVBs contain intraluminal vesicles(ILVs) that are generated by invagination and scission from the limiting membrane of the endosome and mostly are delivered to lysosomes enabling degradation of membrane proteins, such as stimulated growth factor receptors, lysosomal enzymes and lipids. The MVB pathway appears to require the sequential function of ESCRT-O,-I,-II and-III complexes. ESCRT-III proteins mostly dissociate from the invaginating membrane before the ILV is released. The ESCRT machinery also functions in topologically equivalent membrane fission events, such as the terminal stages of cytokinesis(PubMed:21310966). Together with SPAST, the ESCRT-III complex promotes nuclear envelope sealing and mitotic spindle disassembly during late anaphase(PubMed:26040712). ESCRT-III proteins are believed to mediate the necessary vesicle extrusion and/or membrane fission activities, possibly in conjunction with the AAA ATPase VPS4. (Microbial infection) The ESCRT machinery functions in topologically equivalent membrane fission events, such as the budding of enveloped viruses(HIV-1 and other lentiviruses). Involved in HIV-1 p6-and p9-dependent virus release.
-
分子量
- 32 kDa
-
基因ID
- 27243
-
UniProt
- O43633
-
途径
- SARS-CoV-2 Protein Interactome
抗原
-
