电话:
+86 (0512) 65829739
传真:
+86 (010) 6788 5057
电子邮件:
orders@antibodies-online.cn

CHMP2A 抗体

This anti-CHMP2A antibody is a 兔 多克隆 antibody detecting CHMP2A in WB 和 ELISA. Suitable for 人, 大鼠 和 小鼠.
产品编号 ABIN7112645
发货至: 中国

Quick Overview for CHMP2A 抗体 (ABIN7112645)

抗原

See all CHMP2A 抗体
CHMP2A (Charged Multivesicular Body Protein 2A (CHMP2A))

适用

  • 26
  • 20
  • 5
  • 4
  • 4
  • 4
  • 3
  • 3
  • 2
  • 2
  • 1
  • 1
  • 1
  • 1
人, 大鼠, 小鼠

宿主

  • 39
  • 2

克隆类型

  • 41
多克隆

标记

  • 11
  • 5
  • 4
  • 4
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
This CHMP2A antibody is un-conjugated

应用范围

  • 32
  • 15
  • 13
  • 13
  • 10
  • 6
  • 3
  • 2
  • 1
Western Blotting (WB), ELISA
  • 纯化方法

    Immunogen affinity purified

    纯度

    ≥95 % as determined by SDS-PAGE

    免疫原

    chromatin modifying protein 2A

    亚型

    IgG
  • 应用备注

    WB: 1:500-1:2000

    限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

    PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    -20°C for 12 months (Avoid repeated freeze / thaw cycles.)

    有效期

    12 months
  • 抗原

    CHMP2A (Charged Multivesicular Body Protein 2A (CHMP2A))

    别名

    CHMP2A

    背景

    Synonyms:BC2, CHMP2 Background:Probable core component of the endosomal sorting required for transport complex III(ESCRT-III) which is involved in multivesicular bodies(MVBs) formation and sorting of endosomal cargo proteins into MVBs. MVBs contain intraluminal vesicles(ILVs) that are generated by invagination and scission from the limiting membrane of the endosome and mostly are delivered to lysosomes enabling degradation of membrane proteins, such as stimulated growth factor receptors, lysosomal enzymes and lipids. The MVB pathway appears to require the sequential function of ESCRT-O,-I,-II and-III complexes. ESCRT-III proteins mostly dissociate from the invaginating membrane before the ILV is released. The ESCRT machinery also functions in topologically equivalent membrane fission events, such as the terminal stages of cytokinesis(PubMed:21310966). Together with SPAST, the ESCRT-III complex promotes nuclear envelope sealing and mitotic spindle disassembly during late anaphase(PubMed:26040712). ESCRT-III proteins are believed to mediate the necessary vesicle extrusion and/or membrane fission activities, possibly in conjunction with the AAA ATPase VPS4. (Microbial infection) The ESCRT machinery functions in topologically equivalent membrane fission events, such as the budding of enveloped viruses(HIV-1 and other lentiviruses). Involved in HIV-1 p6-and p9-dependent virus release.

    分子量

    32 kDa

    基因ID

    27243

    UniProt

    O43633

    途径

    SARS-CoV-2 Protein Interactome
You are here:
Chat with us!