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CEP63 抗体

CEP63 适用: 人, 小鼠, 大鼠 WB, ELISA, IHC, IF, IP 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN7112613
发货至: 中国
  • 抗原 See all CEP63 抗体
    CEP63 (Centrosomal Protein 63kDa (CEP63))
    适用
    • 30
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    人, 小鼠, 大鼠
    宿主
    • 30
    克隆类型
    • 30
    多克隆
    标记
    • 10
    • 4
    • 3
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This CEP63 antibody is un-conjugated
    应用范围
    Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Immunofluorescence (IF), Immunoprecipitation (IP)
    纯化方法
    Immunogen affinity purified
    纯度
    ≥95 % as determined by SDS-PAGE
    免疫原
    centrosomal protein 63kDa
    亚型
    IgG
    Top Product
    Discover our top product CEP63 Primary Antibody
  • 应用备注
    WB: 1:500-1:2000, IP: 1:200-1:1000, IHC: 1:20-1:200, IF: 1:20-1:200
    限制
    仅限研究用
  • 状态
    Liquid
    缓冲液
    PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    -20 °C
    储存方法
    -20°C for 12 months (Avoid repeated freeze / thaw cycles.)
    有效期
    12 months
  • 抗原
    CEP63 (Centrosomal Protein 63kDa (CEP63))
    别名
    CEP63 (CEP63 产品)
    别名
    4921501M07 antibody, AL450317.13gm1 antibody, AW107703 antibody, CD20R antibody, D9Mgc41 antibody, D9Mgc48e antibody, ET2 antibody, zgc:63548 antibody, Cep63-A antibody, Cep63-B antibody, Xcep63 antibody, centrosomal protein 63 antibody, centrosomal protein 63kDa antibody, centrosomal protein 63kDa L homeolog antibody, CEP63 antibody, SYO3AOP1_1060 antibody, Cep63 antibody, cep63 antibody, cep63.L antibody
    背景
    Synonyms: Background:Required for normal spindle assembly. Plays a key role in mother-centriole-dependent centriole duplication, the function seems also to involve CEP152, CDK5RAP2 and WDR62 through a stepwise assembled complex at the centrosome that recruits CDK2 required for centriole duplication. Reported to be required for centrosomal recruitment of CEP152, however, this function has been questioned(PubMed:21983783, PubMed:26297806). Also recruits CDK1 to centrosomes(PubMed:21406398). Plays a role in DNA damage response. Following DNA damage, such as double-strand breaks(DSBs), is removed from centrosomes, this leads to the inactivation of spindle assembly and delay in mitotic progression(PubMed:21406398).
    分子量
    57-75kd
    基因ID
    80254
    UniProt
    Q96MT8
    途径
    M Phase
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