CEP63 抗体
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北京 101111
Quick Overview for CEP63 抗体 (ABIN7112613)
抗原
See all CEP63 抗体适用
宿主
克隆类型
标记
应用范围
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原理
- CEP63 antibody
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纯化方法
- Immunogen affinity purified
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纯度
- ≥95 % as determined by SDS-PAGE
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免疫原
- centrosomal protein 63 kDaa
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亚型
- IgG
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anti-Centrosomal Protein 63kDa (CEP63) (AA 1-495) antibody
CEP63 适用: 人 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Centrosomal Protein 63kDa (CEP63) (AA 520-548) antibodyCEP63 适用: 人 WB, IHC (p) 宿主: 兔 Polyclonal RB24657 unconjugated
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应用备注
- WB: 1:500-1:2000, IP: 1:200-1:1000, IHC: 1:20-1:200, IF: 1:20-1:200
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid repeated freeze / thaw cycles.
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储存条件
- -20 °C
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储存方法
- -20°C for 12 months
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有效期
- 12 months
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- CEP63 (Centrosomal Protein 63kDa (CEP63))
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别名
- CEP63
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背景
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Synonyms: Centrosomal protein of 63 kDa (Cep63)|CEP63
Background: Required for normal spindle assembly. Plays a key role in mother-centriole-dependent centriole duplication, the function seems also to involve CEP152, CDK5RAP2 and WDR62 through a stepwise assembled complex at the centrosome that recruits CDK2 required for centriole duplication. Reported to be required for centrosomal recruitment of CEP152, however, this function has been questioned(PubMed:21983783, PubMed:26297806). Also recruits CDK1 to centrosomes(PubMed:21406398). Plays a role in DNA damage response. Following DNA damage, such as double-strand breaks(DSBs), is removed from centrosomes, this leads to the inactivation of spindle assembly and delay in mitotic progression(PubMed:21406398).
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分子量
- 57-75 kDa
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基因ID
- 80254
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UniProt
- Q96MT8
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途径
- M Phase
抗原
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