CEP290 抗体
Quick Overview for CEP290 抗体 (ABIN7112607)
抗原
See all CEP290 抗体适用
宿主
克隆类型
标记
应用范围
-
-
原理
- CEP290 antibody
-
纯化方法
- Immunogen affinity purified
-
纯度
- ≥95 % as determined by SDS-PAGE
-
免疫原
- centrosomal protein 290kDa
-
亚型
- IgG
-
-
anti-Centrosomal Protein 290kDa (CEP290) (Internal Region) antibody
Verified CEP290 适用: 人 ELISA, IHC, IF 宿主: 山羊 Polyclonal unconjugated
anti-Centrosomal Protein 290kDa (CEP290) (Internal Region) antibodyVerified CEP290 适用: 人 ELISA, IHC, ICC 宿主: 山羊 Polyclonal unconjugated
anti-Centrosomal Protein 290kDa (CEP290) (Internal Region) antibodyCEP290 适用: 人, 小鼠 ELISA, WB, IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-Centrosomal Protein 290kDa (CEP290) (Internal Region) antibodyCEP290 适用: 人, 小鼠 ELISA, WB 宿主: 兔 Polyclonal unconjugated
anti-Centrosomal Protein 290kDa (CEP290) (AA 950-1050) antibodyCEP290 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
-
-
应用备注
- WB: 1:200-1:2000, IP: 1:500-1:5000, IHC: 1:20-1:200, IF: 1:50-1:500
-
限制
- 仅限研究用
-
-
-
状态
- Liquid
-
缓冲液
- PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,
-
储存液
- Sodium azide
-
注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
-
注意事项
- Avoid repeated freeze / thaw cycles.
-
储存条件
- -20 °C
-
储存方法
- -20°C for 12 months
-
有效期
- 12 months
-
-
- CEP290 (Centrosomal Protein 290kDa (CEP290))
-
别名
- CEP290
-
背景
-
Synonyms: Centrosomal protein of 290 kDa (Cep290)|Bardet-Biedl syndrome 14 protein|Cancer/testis antigen 87 (CT87)|Nephrocystin-6|Tumor antigen se2-2|CEP290|BBS14|KIAA0373|NPHP6
Background: Studies in the Chlamydomonas model system has shown that the ciliary protein CEP290 is a critical component of these Y-link junctions. Additionally, numerous studies have demonstrated that CEP290's function is critical for IFT-in CEP290 knockdown experiments, many proteins that would normally localize to the cilium fail to do so, and cilium formation is disrupted or absent. Mutations in CEP290 are accountable for cases of nephronophthisis, Leber congenital amaurosis and Joubert syndrome. In IF analtsis of HeLa cells, the white arrows show centrosome and cilium staining.
-
分子量
- 290 kDa, 150-180 kDa, 80 kDa, 60 kDa
-
基因ID
- 80184
-
UniProt
- O15078
-
途径
- cAMP Metabolic Process, M Phase
抗原
-
