CENPN 抗体
Quick Overview for CENPN 抗体 (ABIN7112598)
抗原
See all CENPN 抗体适用
宿主
克隆类型
标记
应用范围
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原理
- CENPN antibody
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纯化方法
- Immunogen affinity purified
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纯度
- ≥95 % as determined by SDS-PAGE
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免疫原
- centromere protein N
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亚型
- IgG
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应用备注
- WB: 1:500-1:2000
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid repeated freeze / thaw cycles.
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储存条件
- -20 °C
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储存方法
- -20°C for 12 months
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有效期
- 12 months
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- CENPN (Centromere Protein N (CENPN))
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别名
- CENPN
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背景
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Synonyms: Centromere protein N (CENP-N)|Interphase centromere complex protein 32|CENPN|C16orf60|ICEN32
Background: Component of the CENPA-NAC(nucleosome-associated) complex, a complex that plays a central role in assembly of kinetochore proteins, mitotic progression and chromosome segregation. The CENPA-NAC complex recruits the CENPA-CAD(nucleosome distal) complex and may be involved in incorporation of newly synthesized CENPA into centromeres. CENPN is the first protein to bind specifically to CENPA nucleosomes and the direct binding of CENPA nucleosomes by CENPN is required for centromere assembly. Required for chromosome congression and efficiently align the chromosomes on a metaphase plate.
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分子量
- 40 kDa, 25-30 kDa
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基因ID
- 55839
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UniProt
- Q96H22
抗原
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