CISD2 抗体
Quick Overview for CISD2 抗体 (ABIN7112541)
抗原
See all CISD2 抗体适用
宿主
克隆类型
标记
应用范围
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原理
- CISD2 antibody
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纯化方法
- Immunogen affinity purified
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纯度
- ≥95 % as determined by SDS-PAGE
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免疫原
- CDGSH iron sulfur domain 2
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亚型
- IgG
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应用备注
- WB: 1:500-1:2000, IP: 1:200-1:1000, IHC: 1:20-1:200, IF: 1:20-1:200
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid repeated freeze / thaw cycles.
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储存条件
- -20 °C
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储存方法
- -20°C for 12 months
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有效期
- 12 months
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- CISD2 (CDGSH Iron Sulfur Domain 2 (CISD2))
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别名
- CISD2
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背景
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Synonyms: CDGSH iron-sulfur domain-containing protein 2|Endoplasmic reticulum intermembrane small protein|MitoNEET-related 1 protein (Miner1)|Nutrient-deprivation autophagy factor-1 (NAF-1)|CISD2|CDGSH2|ERIS|ZCD2
Background: Regulator of autophagy that contributes to antagonize BECN1-mediated cellular autophagy at the endoplasmic reticulum. Participates in the interaction of BCL2 with BECN1 and is required for BCL2-mediated depression of endoplasmic reticulum Ca(2+) stores during autophagy. Contributes to BIK-initiated autophagy, while it is not involved in BIK-dependent activation of caspases. Involved in life span control, probably via its function as regulator of autophagy.
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分子量
- 13-15 kDa
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基因ID
- 493856
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UniProt
- Q8N5K1
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途径
- Activation of Innate immune Response
抗原
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