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CISD2 抗体

This anti-CISD2 antibody is a 兔 多克隆 antibody detecting CISD2 in WB, ELISA, IHC, IF 和 IP. Suitable for 人, 小鼠 和 大鼠.
产品编号 ABIN7112541
发货至: 中国

Quick Overview for CISD2 抗体 (ABIN7112541)

抗原

See all CISD2 抗体
CISD2 (CDGSH Iron Sulfur Domain 2 (CISD2))

适用

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人, 小鼠, 大鼠

宿主

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克隆类型

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多克隆

标记

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This CISD2 antibody is un-conjugated

应用范围

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Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Immunofluorescence (IF), Immunoprecipitation (IP)
  • 原理

    CISD2 antibody

    纯化方法

    Immunogen affinity purified

    纯度

    ≥95 % as determined by SDS-PAGE

    免疫原

    CDGSH iron sulfur domain 2

    亚型

    IgG
  • 应用备注

    WB: 1:500-1:2000, IP: 1:200-1:1000, IHC: 1:20-1:200, IF: 1:20-1:200

    限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

    PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    注意事项

    Avoid repeated freeze / thaw cycles.

    储存条件

    -20 °C

    储存方法

    -20°C for 12 months

    有效期

    12 months
  • 抗原

    CISD2 (CDGSH Iron Sulfur Domain 2 (CISD2))

    别名

    CISD2

    背景

    Synonyms: CDGSH iron-sulfur domain-containing protein 2|Endoplasmic reticulum intermembrane small protein|MitoNEET-related 1 protein (Miner1)|Nutrient-deprivation autophagy factor-1 (NAF-1)|CISD2|CDGSH2|ERIS|ZCD2

    Background: Regulator of autophagy that contributes to antagonize BECN1-mediated cellular autophagy at the endoplasmic reticulum. Participates in the interaction of BCL2 with BECN1 and is required for BCL2-mediated depression of endoplasmic reticulum Ca(2+) stores during autophagy. Contributes to BIK-initiated autophagy, while it is not involved in BIK-dependent activation of caspases. Involved in life span control, probably via its function as regulator of autophagy.

    分子量

    13-15 kDa

    基因ID

    493856

    UniProt

    Q8N5K1

    途径

    Activation of Innate immune Response
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