CDC14B 抗体
Quick Overview for CDC14B 抗体 (ABIN7112534)
抗原
See all CDC14B 抗体适用
宿主
克隆类型
标记
应用范围
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原理
- CDC14B antibody
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纯化方法
- Immunogen affinity purified
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纯度
- ≥95 % as determined by SDS-PAGE
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免疫原
- CDC14 cell division cycle 14 homolog B
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亚型
- IgG
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anti-CDC14 Cell Division Cycle 14B (CDC14B) (AA 360-459) antibody
CDC14B 适用: 人 WB, ELISA 宿主: 小鼠 Polyclonal unconjugated
anti-CDC14 Cell Division Cycle 14B (CDC14B) (AA 1-471) antibodyCDC14B 适用: 人 WB, IP 宿主: 兔 Polyclonal unconjugated
anti-CDC14 Cell Division Cycle 14B (CDC14B) (AA 1-471) antibodyCDC14B 适用: 人 WB, IF 宿主: 小鼠 Polyclonal unconjugated
anti-CDC14 Cell Division Cycle 14B (CDC14B) (AA 65-160) antibodyCDC14B 适用: 人, 小鼠, 大鼠 IF (cc), IF (p), ELISA, IHC (fro), IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-CDC14 Cell Division Cycle 14B (CDC14B) (AA 188-215) antibodyCDC14B 适用: 人 WB, FACS 宿主: 兔 Polyclonal RB16909 unconjugated
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应用备注
- WB: 1:500-1:2000
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid repeated freeze / thaw cycles.
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储存条件
- -20 °C
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储存方法
- -20°C for 12 months
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有效期
- 12 months
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- CDC14B (CDC14 Cell Division Cycle 14B (CDC14B))
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别名
- CDC14B
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背景
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Synonyms: Dual specificity protein phosphatase CDC14B|CDC14 cell division cycle 14 homolog B|CDC14B
Background: Dual-specificity phosphatase involved in DNA damage response. Essential regulator of the G2 DNA damage checkpoint: following DNA damage, translocates to the nucleus and dephosphorylates FZR1/CDH1, a key activator of the anaphase promoting complex/cyclosome(APC/C). Dephosphorylates SIRT2 around early anaphase. Dephosphorylation of FZR1/CDH1 activates the APC/C, leading to the ubiquitination of PLK1, preventing entry into mitosis. Preferentially dephosphorylates proteins modified by proline-directed kinases.
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分子量
- 56 kDa
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基因ID
- 8555
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UniProt
- O60729
抗原
-
