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ADGRE5 (AA 211-308) 抗体

This 兔 多克隆 antibody specifically detects ADGRE5 in WB, ELISA 和 IHC. It exhibits reactivity toward 人, 小鼠 和 大鼠.
产品编号 ABIN7112530
发货至: 中国
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Quick Overview for ADGRE5 (AA 211-308) 抗体 (ABIN7112530)

抗原

ADGRE5

适用

人, 小鼠, 大鼠

宿主

  • 4
  • 1

克隆类型

  • 5
多克隆

标记

  • 5
非结合性

应用范围

  • 5
  • 3
  • 3
  • 1
Western Blotting (WB), ELISA, Immunohistochemistry (IHC)
  • 抗原表位

    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 211-308

    原理

    ADGRE5 antibody

    纯化方法

    Immunogen affinity purified

    纯度

    ≥95 % as determined by SDS-PAGE

    免疫原

    Immunogen sequence: 211-308aa

    Immunogen: CD97 molecule

    亚型

    IgG
  • 应用备注

    WB: 1:200 - 1:2000, IHC: 1:50 - 1:100

    限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

    PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    注意事项

    Avoid repeated freeze / thaw cycles.

    储存条件

    -20 °C

    储存方法

    -20°C for 12 months

    有效期

    12 months
  • 抗原

    ADGRE5

    背景

    Synonyms: Adhesion G protein-coupled receptor E5|Leukocyte antigen CD97|Adhesion G protein-coupled receptor E5 subunit alpha|Adhesion G protein-coupled receptor E5 subunit beta|ADGRE5|CD97

    Background: This gene encodes a member of the EGF-TM7 subfamily of adhesion G protein-coupled receptors, which mediate cell-cell interactions. These proteins are cleaved by self-catalytic proteolysis into a large extracellular subunit and seven-span transmembrane subunit, which associate at the cell surface as a receptor complex. The encoded protein may play a role in cell adhesion as well as leukocyte recruitment, activation and migration, and contains multiple extracellular EGF-like repeats which mediate binding to chondroitin sulfate and the cell surface complement regulatory protein CD55. Expression of this gene may play a role in the progression of several types of cancer. Alternatively spliced transcript variants encoding multiple isoforms with 3 to 5 EGF-like repeats have been observed for this gene. This gene is found in a cluster with other EGF-TM7 genes on the short arm of chromosome 19.

    分子量

    105 kDa

    基因ID

    976

    UniProt

    P48960
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