CD2AP 抗体
Quick Overview for CD2AP 抗体 (ABIN7112459)
抗原
See all CD2AP (Cd2ap) 抗体适用
宿主
克隆类型
标记
应用范围
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原理
- CD2AP antibody
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纯化方法
- Immunogen affinity purified
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纯度
- ≥95 % as determined by SDS-PAGE
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免疫原
- CD2-associated protein
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亚型
- IgG
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应用备注
- WB: 1:500-1:2000, IP: 1:500-1:1000, IF: 1:10-1:100
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid repeated freeze / thaw cycles.
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储存条件
- -20 °C
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储存方法
- -20°C for 12 months
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有效期
- 12 months
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- CD2AP (Cd2ap) (CD2-Associated Protein (Cd2ap))
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别名
- CD2AP
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背景
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Synonyms: CD2-associated protein|Adapter protein CMS|Cas ligand with multiple SH3 domains|CD2AP
Background: Seems to act as an adapter protein between membrane proteins and the actin cytoskeleton. In collaboration with CBLC, modulates the rate of RET turnover and may act as regulatory checkpoint that limits the potency of GDNF on neuronal survival. Controls CBLC function, converting it from an inhibitor to a promoter of RET degradation. May play a role in receptor clustering and cytoskeletal polarity in the junction between T-cell and antigen-presenting cell. May anchor the podocyte slit diaphragm to the actin cytoskeleton in renal glomerolus. Also required for cytokinesis.
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分子量
- 70 kDa
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基因ID
- 23607
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UniProt
- Q9Y5K6
抗原
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