CNOT7 抗体
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- 抗原 See all CNOT7 抗体
- CNOT7 (CCR4-NOT Transcription Complex, Subunit 7 (CNOT7))
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适用
- 人, 小鼠, 大鼠
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This CNOT7 antibody is un-conjugated
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应用范围
- Western Blotting (WB), ELISA, Immunoprecipitation (IP)
- 纯化方法
- Immunogen affinity purified
- 纯度
- ≥95 % as determined by SDS-PAGE
- 免疫原
- CCR4-NOT transcription complex, subunit 7
- 亚型
- IgG
- Top Product
- Discover our top product CNOT7 Primary Antibody
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- 应用备注
- WB: 1:500-1:2000, IP: 1:200-1:2000
- 限制
- 仅限研究用
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- 状态
- Liquid
- 缓冲液
- PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- -20 °C
- 储存方法
- -20°C for 12 months (Avoid repeated freeze / thaw cycles.)
- 有效期
- 12 months
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- 抗原
- CNOT7 (CCR4-NOT Transcription Complex, Subunit 7 (CNOT7))
- 别名
- CNOT7 (CNOT7 产品)
- 背景
- Synonyms:CAF1 Background:Has 3'-5' poly(A) exoribonuclease activity for synthetic poly(A) RNA substrate. Its function seems to be partially redundant with that of CNOT8. Catalytic component of the CCR4-NOT complex which is one of the major cellular mRNA deadenylases and is linked to various cellular processes including bulk mRNA degradation, miRNA-mediated repression, translational repression during translational initiation and general transcription regulation. During miRNA-mediated repression the complex seems also to act as translational repressor during translational initiation. Additional complex functions may be a consequence of its influence on mRNA expression. Associates with members of the BTG family such as TOB1 and BTG2 and is required for their anti-proliferative activity.
- 分子量
- 33-35 kDa
- 基因ID
- 29883
- UniProt
- Q9UIV1
- 途径
- Ribonucleoprotein Complex Subunit Organization
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