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CNOT7 抗体

This anti-CNOT7 antibody is a 兔 多克隆 antibody detecting CNOT7 in WB, ELISA 和 IP. Suitable for 人, 小鼠 和 大鼠.
产品编号 ABIN7112436
发货至: 中国

Quick Overview for CNOT7 抗体 (ABIN7112436)

抗原

See all CNOT7 抗体
CNOT7 (CCR4-NOT Transcription Complex, Subunit 7 (CNOT7))

适用

  • 39
  • 19
  • 7
  • 4
  • 4
  • 4
  • 3
  • 3
  • 3
  • 3
  • 3
  • 3
  • 2
  • 2
  • 2
  • 2
  • 1
人, 小鼠, 大鼠

宿主

  • 32
  • 7

克隆类型

  • 33
  • 6
多克隆

标记

  • 24
  • 2
  • 2
  • 2
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
This CNOT7 antibody is un-conjugated

应用范围

  • 29
  • 21
  • 14
  • 13
  • 7
  • 3
  • 2
  • 1
Western Blotting (WB), ELISA, Immunoprecipitation (IP)
  • 原理

    CNOT7 antibody

    纯化方法

    Immunogen affinity purified

    纯度

    ≥95 % as determined by SDS-PAGE

    免疫原

    CCR4-NOT transcription complex, subunit 7

    亚型

    IgG
  • 应用备注

    WB: 1:500-1:2000, IP: 1:200-1:2000

    限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

    PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    注意事项

    Avoid repeated freeze / thaw cycles.

    储存条件

    -20 °C

    储存方法

    -20°C for 12 months

    有效期

    12 months
  • 抗原

    CNOT7 (CCR4-NOT Transcription Complex, Subunit 7 (CNOT7))

    别名

    CNOT7

    背景

    Synonyms: CCR4-NOT transcription complex subunit 7|BTG1-binding factor 1|CCR4-associated factor 1 (CAF-1)|Caf1a|CNOT7|CAF1

    Background: Has 3'-5' poly(A) exoribonuclease activity for synthetic poly(A) RNA substrate. Its function seems to be partially redundant with that of CNOT8. Catalytic component of the CCR4-NOT complex which is one of the major cellular mRNA deadenylases and is linked to various cellular processes including bulk mRNA degradation, miRNA-mediated repression, translational repression during translational initiation and general transcription regulation. During miRNA-mediated repression the complex seems also to act as translational repressor during translational initiation. Additional complex functions may be a consequence of its influence on mRNA expression. Associates with members of the BTG family such as TOB1 and BTG2 and is required for their anti-proliferative activity.

    分子量

    33-35 kDa

    基因ID

    29883

    UniProt

    Q9UIV1

    途径

    Ribonucleoprotein Complex Subunit Organization
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