CTCFL 抗体 (AA 361-663)
Quick Overview for CTCFL 抗体 (AA 361-663) (ABIN7112427)
抗原
See all CTCFL 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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抗原表位
- AA 361-663
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原理
- CTCFL antibody
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纯化方法
- Protein A+G purification
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纯度
- ≥95 % as determined by SDS-PAGE
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免疫原
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Immunogen sequence: 361-663aa
Immunogen: CCCTC-binding factor(zinc finger protein)-like
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亚型
- IgG1
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应用备注
- WB: 1:500-1:2000, IF: 1:10-1:100
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid repeated freeze / thaw cycles.
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储存条件
- -20 °C
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储存方法
- -20°C for 12 months
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有效期
- 12 months
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- CTCFL (CCCTC-Binding Factor (Zinc Finger Protein)-Like (CTCFL))
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别名
- CTCFL
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背景
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Synonyms: Transcriptional repressor CTCFL|Brother of the regulator of imprinted sites|CCCTC-binding factor|CTCF paralog|CTCF-like protein|Cancer/testis antigen 27 (CT27)|Zinc finger protein CTCF-T|CTCFL|BORIS
Background: CTCFL, also named BORIS(for brother of the regulator of imprinted sites) is a paralogue of the 11 zinc-finger transcription factor, CTCF. It is predominantly expressed in spermatocytes in the testis, also can be found in tumors and cancer cell lines. It mainly participates in insulator function, nuclear architecture and transcriptional control, which probably acts by recruiting epigenetic chromatin modifiers. It has a key role in gene imprinting in male germline, by participating in the establishment of differential methylation at the IGF2/H19 imprinted control region(ICR). Directly binds the unmethylated H19 ICR and recruits the PRMT7 methyltransferase, leading to methylate histone H4 'Arg-3' to form H4R3sme2.
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分子量
- 75 kDa
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基因ID
- 140690
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UniProt
- Q8NI51
抗原
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