CES1 抗体
Quick Overview for CES1 抗体 (ABIN7112300)
抗原
See all CES1 抗体适用
宿主
克隆类型
标记
应用范围
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原理
- CES1 antibody
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纯化方法
- Immunogen affinity purified
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纯度
- ≥95 % as determined by SDS-PAGE
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免疫原
- carboxylesterase 1 (monocyte/macrophage serine esterase 1)
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亚型
- IgG
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应用备注
- WB: 1:500 - 1:2000, IHC: 1:50 - 1:200
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid repeated freeze / thaw cycles.
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储存条件
- -20 °C
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储存方法
- -20°C for 12 months
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有效期
- 12 months
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- CES1 (Carboxylesterase 1 (CES1))
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别名
- CES1
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背景
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Synonyms: Liver carboxylesterase 1|Acyl-coenzyme A:cholesterol acyltransferase (ACAT)|Brain carboxylesterase hBr1|Carboxylesterase 1 (CE-1, hCE-1)|Cholesteryl ester hydrolase (CEH)|Cocaine carboxylesterase|Egasyn|HMSE|Methylumbelliferyl-acetate deacetylase 1|Monocyte/macrophage serine esterase|Retinyl ester hydrolase (REH)|Serine esterase 1|Triacylglycerol hydrolase (TGH)|CES1|CES2|SES1
Background: This gene encodes a member of the carboxylesterase large family. The family members are responsible for the hydrolysis or transesterification of various xenobiotics, such as cocaine and heroin, and endogenous substrates with ester, thioester, or amide bonds. They may participate in fatty acyl and cholesterol ester metabolism, and may play a role in the blood-brain barrier system. This enzyme is the major liver enzyme and functions in liver drug clearance. Mutations of this gene cause carboxylesterase 1 deficiency. Three transcript variants encoding three different isoforms have been found for this gene.
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分子量
- 62 kDa
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基因ID
- 1066
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UniProt
- P23141
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途径
- Monocarboxylic Acid Catabolic Process
抗原
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