Calsyntenin 1 抗体
Quick Overview for Calsyntenin 1 抗体 (ABIN7112234)
抗原
See all Calsyntenin 1 (CLSTN1) 抗体适用
宿主
克隆类型
标记
应用范围
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原理
- CLSTN1 antibody
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纯化方法
- Immunogen affinity purified
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纯度
- ≥95 % as determined by SDS-PAGE
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免疫原
- calsyntenin 1
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亚型
- IgG
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anti-Calsyntenin 1 (CLSTN1) (AA 35-84) antibody
CLSTN1 适用: 人, 小鼠, 大鼠, Cow, 豚鼠, 马, 兔, 斑马鱼, Bat, 猴, Pig WB, IHC, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Calsyntenin 1 (CLSTN1) (AA 1-971) antibodyCLSTN1 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
anti-Calsyntenin 1 (CLSTN1) (C-Term) antibodyCLSTN1 适用: 人, 小鼠 WB, ELISA, IHC, IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-Calsyntenin 1 (CLSTN1) (AA 29-350) antibodyCLSTN1 适用: 人 WB, IF 宿主: 兔 Polyclonal unconjugated
anti-Calsyntenin 1 (CLSTN1) antibodyKD Validated CLSTN1 适用: 人, 小鼠 WB, IHC, IF, ICC 宿主: 兔 Monoclonal unconjugated Recombinant Antibody
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应用备注
- WB: 1:500-1:2000
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid repeated freeze / thaw cycles.
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储存条件
- -20 °C
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储存方法
- -20°C for 12 months
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有效期
- 12 months
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- Calsyntenin 1 (CLSTN1)
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别名
- CLSTN1
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背景
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Synonyms: Calsyntenin-1|Alcadein-alpha (Alc-alpha)|Alzheimer-related cadherin-like protein|Non-classical cadherin XB31alpha|Soluble Alc-alpha (SAlc-alpha)|CTF1-alpha Alternative names: C-terminal fragment 1-alpha|CLSTN1|CS1|KIAA0911
Background: Induces KLC1 association with vesicles and functions as a cargo in axonal anterograde transport. Complex formation with APBA2 and APP, stabilizes APP metabolism and enhances APBA2-mediated suppression of beta-APP40 secretion, due to the retardation of intracellular APP maturation. In complex with APBA2 and C99, a C-terminal APP fragment, abolishes C99 interaction with PSEN1 and thus APP C99 cleavage by gamma-secretase, most probably through stabilization of the direct interaction between APBA2 and APP. The intracellular fragment AlcICD suppresses APBB1-dependent transactivation stimulated by APP C-terminal intracellular fragment(AICD), most probably by competing with AICD for APBB1-binding. May modulate calcium-mediated postsynaptic signals(By similarity).
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分子量
- 109 kDa
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基因ID
- 22883
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UniProt
- O94985
抗原
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