CAMKK2 抗体
Quick Overview for CAMKK2 抗体 (ABIN7112196)
抗原
See all CAMKK2 抗体适用
宿主
克隆类型
标记
应用范围
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原理
- CAMKK2 antibody
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纯化方法
- Immunogen affinity purified
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纯度
- ≥95 % as determined by SDS-PAGE
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免疫原
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Immunogen sequence: 1-353
Immunogen: calcium/calmodulin-dependent protein kinase kinase 2, beta
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亚型
- IgG
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应用备注
- WB: 1:500-1:2000, IF: 1:20-1:200, IHC: 1:20-1:200
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid repeated freeze / thaw cycles.
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储存条件
- -20 °C
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储存方法
- -20°C for 12 months
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有效期
- 12 months
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- CAMKK2 (Calcium/calmodulin-Dependent Protein Kinase Kinase 2, beta (CAMKK2))
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别名
- CAMKK2
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背景
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Synonyms: Calcium/calmodulin-dependent protein kinase kinase 2 (CaM-KK 2, CaM-kinase kinase 2, CaMKK 2)|Calcium/calmodulin-dependent protein kinase kinase beta (CaM-KK beta, CaM-kinase kinase beta, CaMKK beta)|CAMKK2|CAMKKB|KIAA0787
Background: Calcium/calmodulin-dependent protein kinase belonging to a proposed calcium-triggered signaling cascade involved in a number of cellular processes. Isoform 1, isoform 2 and isoform 3 phosphorylate CAMK1 and CAMK4. Isoform 3 phosphorylates CAMK1D. Isoform 4, isoform 5 and isoform 6 lacking part of the calmodulin-binding domain are inactive. Efficiently phosphorylates 5'-AMP-activated protein kinase(AMPK) trimer, including that consisting of PRKAA1, PRKAB1 and PRKAG1. This phosphorylation is stimulated in response to Ca(2+) signals(By similarity). Seems to be involved in hippocampal activation of CREB1(By similarity). May play a role in neurite growth. Isoform 3 may promote neurite elongation, while isoform 1 may promoter neurite branching.
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分子量
- 55-60 kDa
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基因ID
- 10645
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UniProt
- Q96RR4
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途径
- AMPK Signaling
抗原
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