BIN1 抗体
Quick Overview for BIN1 抗体 (ABIN7112069)
抗原
See all BIN1 抗体适用
宿主
克隆类型
标记
应用范围
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原理
- BIN1 antibody
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纯化方法
- Immunogen affinity purified
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纯度
- ≥95 % as determined by SDS-PAGE
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免疫原
- bridging integrator 1
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亚型
- IgG
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anti-Bridging Integrator 1 (BIN1) (AA 189-398) antibody
BIN1 适用: 人, 小鼠 WB, IHC, ELISA, FACS 宿主: 小鼠 Monoclonal 3B6F10 unconjugated
anti-Bridging Integrator 1 (BIN1) (AA 230-409) antibodyBIN1 适用: 人 WB, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Bridging Integrator 1 (BIN1) antibodyBIN1 适用: 人, 大鼠 WB, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Bridging Integrator 1 (BIN1) antibodyBIN1 适用: 人 WB, IHC, IF, ICC, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Bridging Integrator 1 (BIN1) (AA 189-398) antibodyBIN1 适用: 人, 小鼠 WB, ELISA, FACS 宿主: 小鼠 Monoclonal 3B6A4 unconjugated
anti-Bridging Integrator 1 (BIN1) (AA 414-593) antibodyBIN1 适用: 人 IHC, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Bridging Integrator 1 (BIN1) (AA 1-482) antibodyBIN1 适用: 人 WB, IF 宿主: 兔 Polyclonal unconjugated
anti-Bridging Integrator 1 (BIN1) (AA 355-454) antibodyBIN1 适用: 人 WB, ELISA 宿主: 小鼠 Monoclonal 2C7 unconjugated
anti-Bridging Integrator 1 (BIN1) antibodyBIN1 适用: 小鼠 WB, IHC, ELISA, IP 宿主: 小鼠 Monoclonal 2F11 unconjugated
anti-Bridging Integrator 1 (BIN1) antibodyBIN1 适用: 人, 小鼠 WB, IHC, ELISA, IP, FACS 宿主: 小鼠 Monoclonal 99D unconjugated
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应用备注
- WB: 1:500 - 1:2000, IHC: 1:50 - 1:200, IF: 1:20 - 1:50
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid repeated freeze / thaw cycles.
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储存条件
- -20 °C
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储存方法
- -20°C for 12 months
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有效期
- 12 months
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- BIN1 (Bridging Integrator 1 (BIN1))
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别名
- BIN1
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背景
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Synonyms: Myc box-dependent-interacting protein 1|Amphiphysin II|Amphiphysin-like protein|Box-dependent myc-interacting protein 1|Bridging integrator 1|BIN1|AMPHL
Background: This gene encodes several isoforms of a nucleocytoplasmic adaptor protein, one of which was initially identified as a MYC-interacting protein with features of a tumor suppressor. Isoforms that are expressed in the central nervous system may be involved in synaptic vesicle endocytosis and may interact with dynamin, synaptojanin, endophilin, and clathrin. Isoforms that are expressed in muscle and ubiquitously expressed isoforms localize to the cytoplasm and nucleus and activate a caspase-independent apoptotic process. Studies in mouse suggest that this gene plays an important role in cardiac muscle development. Alternate splicing of the gene results in several transcript variants encoding different isoforms. Aberrant splice variants expressed in tumor cell lines have also been described.
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分子量
- 65 kDa
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基因ID
- 274
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UniProt
- O00499
抗原
-
