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BCCIP 抗体

BCCIP 适用: 人, 小鼠, 大鼠 WB, IHC, ELISA 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN7112053
发货至: 中国
  • 抗原 See all BCCIP 抗体
    BCCIP (BRCA2 and CDKN1A Interacting Protein (BCCIP))
    适用
    人, 小鼠, 大鼠
    宿主
    • 29
    • 5
    克隆类型
    • 33
    • 1
    多克隆
    标记
    • 20
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This BCCIP antibody is un-conjugated
    应用范围
    • 15
    • 14
    • 13
    • 8
    • 7
    • 7
    • 6
    • 4
    • 3
    • 3
    • 2
    • 1
    Western Blotting (WB), Immunohistochemistry (IHC), ELISA
    纯化方法
    Immunogen affinity purified
    纯度
    ≥95 % as determined by SDS-PAGE
    免疫原
    BRCA2 and CDKN1A interacting protein
    亚型
    IgG
    Top Product
    Discover our top product BCCIP Primary Antibody
  • 应用备注
    WB: 1:500 - 1:2000, IHC: 1:100 - 1:200
    限制
    仅限研究用
  • 状态
    Liquid
    缓冲液
    PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3 ,
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    -20 °C
    储存方法
    -20°C for 12 months (Avoid repeated freeze / thaw cycles.)
    有效期
    12 months
  • 抗原
    BCCIP (BRCA2 and CDKN1A Interacting Protein (BCCIP))
    别名
    BCCIP (BCCIP 产品)
    别名
    zgc:110272 antibody, mp:zf637-1-000774 antibody, BCCIP antibody, DKFZp459K2416 antibody, MGC82792 antibody, tok-1 antibody, MGC89311 antibody, TOK-1 antibody, TOK1 antibody, 1110013J05Rik antibody, BRCA2 and CDKN1A interacting protein antibody, BRCA2 and CDKN1A interacting protein L homeolog antibody, BCCIP antibody, bccip antibody, bccip.L antibody, Bccip antibody
    背景
    Synonyms:TOK1 Background:This gene product was isolated on the basis of its interaction with BRCA2 and p21 proteins. It is an evolutionarily conserved nuclear protein with multiple interacting domains. The N-terminal half shares moderate homology with regions of calmodulin and M-calpain, suggesting that it may also bind calcium. Functional studies indicate that this protein may be an important cofactor for BRCA2 in tumor suppression, and a modulator of CDK2 kinase activity via p21. This protein has also been implicated in the regulation of BRCA2 and RAD51 nuclear focus formation, double-strand break-induced homologous recombination, and cell cycle progression. Multiple transcript variants encoding different isoforms have been described for this gene.
    分子量
    50 kDa
    基因ID
    56647
    UniProt
    Q9P287
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