BCCIP 抗体
Quick Overview for BCCIP 抗体 (ABIN7112053)
抗原
See all BCCIP 抗体适用
宿主
克隆类型
标记
应用范围
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原理
- BCCIP antibody
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纯化方法
- Immunogen affinity purified
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纯度
- ≥95 % as determined by SDS-PAGE
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免疫原
- BRCA2 and CDKN1A interacting protein
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亚型
- IgG
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anti-BRCA2 and CDKN1A Interacting Protein (BCCIP) (AA 1-314) antibody
BCCIP 适用: 人 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-BRCA2 and CDKN1A Interacting Protein (BCCIP) (C-Term) antibodyBCCIP 适用: 人 WB, IF, IHC (p), ICC 宿主: 兔 Polyclonal unconjugated
anti-BRCA2 and CDKN1A Interacting Protein (BCCIP) (AA 1-322) antibodyBCCIP 适用: 人 WB, IF 宿主: 小鼠 Polyclonal unconjugated
anti-BRCA2 and CDKN1A Interacting Protein (BCCIP) (AA 1-314) antibodyBCCIP 适用: 人 WB, IF 宿主: 小鼠 Polyclonal unconjugated
anti-BRCA2 and CDKN1A Interacting Protein (BCCIP) (C-Term) antibodyBCCIP 适用: 人 WB, ELISA, IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-BRCA2 and CDKN1A Interacting Protein (BCCIP) (AA 210-314) antibodyBCCIP 适用: 人 WB, ELISA 宿主: 小鼠 Polyclonal unconjugated
anti-BRCA2 and CDKN1A Interacting Protein (BCCIP) antibodyBCCIP 适用: 人, 小鼠, 大鼠 IHC 宿主: 兔 Polyclonal unconjugated
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应用备注
- WB: 1:500 - 1:2000, IHC: 1:100 - 1:200
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid repeated freeze / thaw cycles.
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储存条件
- -20 °C
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储存方法
- -20°C for 12 months
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有效期
- 12 months
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- BCCIP (BRCA2 and CDKN1A Interacting Protein (BCCIP))
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别名
- BCCIP
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背景
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Synonyms: BRCA2 and CDKN1A-interacting protein|P21- and CDK-associated protein 1|Protein TOK-1|BCCIP|TOK1
Background: This gene product was isolated on the basis of its interaction with BRCA2 and p21 proteins. It is an evolutionarily conserved nuclear protein with multiple interacting domains. The N-terminal half shares moderate homology with regions of calmodulin and M-calpain, suggesting that it may also bind calcium. Functional studies indicate that this protein may be an important cofactor for BRCA2 in tumor suppression, and a modulator of CDK2 kinase activity via p21. This protein has also been implicated in the regulation of BRCA2 and RAD51 nuclear focus formation, double-strand break-induced homologous recombination, and cell cycle progression. Multiple transcript variants encoding different isoforms have been described for this gene.
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分子量
- 50 kDa
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基因ID
- 56647
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UniProt
- Q9P287
抗原
-
