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BEX2 抗体

BEX2 适用: 人, 小鼠, 大鼠 ELISA, IHC, WB 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN7112040
发货至: 中国
  • 抗原 See all BEX2 抗体
    BEX2 (Brain Expressed X-Linked 2 (BEX2))
    适用
    人, 小鼠, 大鼠
    宿主
    • 14
    克隆类型
    • 14
    多克隆
    标记
    • 4
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This BEX2 antibody is un-conjugated
    应用范围
    • 6
    • 3
    • 2
    • 1
    ELISA, Immunohistochemistry (IHC), Western Blotting (WB)
    纯化方法
    Immunogen affinity purified
    纯度
    ≥95 % as determined by SDS-PAGE
    免疫原
    brain expressed X-linked 2
    亚型
    IgG
    Top Product
    Discover our top product BEX2 Primary Antibody
  • 应用备注
    WB: 1:500-1:1000, IHC: 1:20-1:200
    限制
    仅限研究用
  • 状态
    Liquid
    缓冲液
    PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    -20 °C
    储存方法
    -20°C for 12 months (Avoid repeated freeze / thaw cycles.)
    有效期
    12 months
  • 抗原
    BEX2 (Brain Expressed X-Linked 2 (BEX2))
    别名
    BEX2 (BEX2 产品)
    别名
    BEX1 antibody, DJ79P11.1 antibody, AL024066 antibody, Bex1 antibody, EG2RVC antibody, brain expressed X-linked 2 antibody, BEX2 antibody, Bex2 antibody
    背景
    Synonyms:BEX1, BEX1/2, BEX2, brain expressed X linked 2, hBex2, Protein BEX2 Background:Regulator of mitochondrial apoptosis and G1 cell cycle in breast cancer. Protects the breast cancer cells against mitochondrial apoptosis and this effect is mediated through the modulation of BCL2 protein family, which involves the positive regulation of anti-apoptotic member BCL2 and the negative regulation of pro-apoptotic members BAD, BAK1 and PUMA. Required for the normal cell cycle progression during G1 in breast cancer cells through the regulation of CCND1 and CDKN1A. Regulates the level of PP2A regulatory subunit B and PP2A phosphatase activity. The homology between human BEX1 and BEX2 is 94 % . This antibody detects both BEX1 and BEX2.
    分子量
    10-15 kDa
    基因ID
    84707
    UniProt
    Q9BXY8
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