BEX2 抗体
Quick Overview for BEX2 抗体 (ABIN7112040)
抗原
See all BEX2 抗体适用
宿主
克隆类型
标记
应用范围
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原理
- BEX2 antibody
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纯化方法
- Immunogen affinity purified
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纯度
- ≥95 % as determined by SDS-PAGE
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免疫原
- brain expressed X-linked 2
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亚型
- IgG
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anti-Brain Expressed X-Linked 2 (BEX2) (AA 1-128) antibody
BEX2 适用: 人 ELISA, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Brain Expressed X-Linked 2 (BEX2) antibodyBEX2 适用: 人 ELISA, IHC 宿主: 兔 Polyclonal unconjugated
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应用备注
- WB: 1:500-1:1000, IHC: 1:20-1:200
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid repeated freeze / thaw cycles.
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储存条件
- -20 °C
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储存方法
- -20°C for 12 months
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有效期
- 12 months
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- BEX2 (Brain Expressed X-Linked 2 (BEX2))
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别名
- BEX2
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背景
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Synonyms: Protein BEX2|Brain-expressed X-linked protein 2 (hBex2)|BEX2
Background: Regulator of mitochondrial apoptosis and G1 cell cycle in breast cancer. Protects the breast cancer cells against mitochondrial apoptosis and this effect is mediated through the modulation of BCL2 protein family, which involves the positive regulation of anti-apoptotic member BCL2 and the negative regulation of pro-apoptotic members BAD, BAK1 and PUMA. Required for the normal cell cycle progression during G1 in breast cancer cells through the regulation of CCND1 and CDKN1A. Regulates the level of PP2A regulatory subunit B and PP2A phosphatase activity. The homology between human BEX1 and BEX2 is 94 % . This antibody detects both BEX1 and BEX2.
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分子量
- 10-15 kDa
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基因ID
- 84707
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UniProt
- Q9BXY8
抗原
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