BVES 抗体
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北京 101111
Quick Overview for BVES 抗体 (ABIN7112013)
抗原
See all BVES 抗体适用
宿主
克隆类型
标记
应用范围
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原理
- BVES antibody
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纯化方法
- Immunogen affinity purified
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纯度
- ≥95 % as determined by SDS-PAGE
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免疫原
- blood vessel epicardial substance
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亚型
- IgG
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anti-Blood Vessel Epicardial Substance (BVES) (AA 262-360) antibody
BVES 适用: 人 WB, ELISA 宿主: 小鼠 Monoclonal 3F7 unconjugated
anti-Blood Vessel Epicardial Substance (BVES) (AA 241-360) antibodyBVES 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
anti-Blood Vessel Epicardial Substance (BVES) (AA 241-360) antibodyBVES 适用: 人 ELISA, IF 宿主: 兔 Polyclonal unconjugated
anti-Blood Vessel Epicardial Substance (BVES) (AA 262-360) antibodyBVES 适用: 人 WB, ELISA 宿主: 小鼠 Polyclonal unconjugated
anti-Blood Vessel Epicardial Substance (BVES) (AA 251-300) antibodyBVES 适用: 人, 小鼠, 大鼠, Cow, 犬, 豚鼠, 马, 兔, Bat, 小鸡, 猴, Pig WB 宿主: 兔 Polyclonal unconjugated
anti-Blood Vessel Epicardial Substance (BVES) (AA 313-342), (C-Term) antibodyBVES 适用: 人 WB, IHC (p) 宿主: 兔 Polyclonal RB32739 unconjugated
anti-Blood Vessel Epicardial Substance (BVES) (AA 312-342), (C-Term) antibodyBVES 适用: 人 WB, EIA 宿主: 兔 Polyclonal unconjugated
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应用备注
- WB: 1:100-1:1000, IHC: 1:20-1:200
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid repeated freeze / thaw cycles.
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储存条件
- -20 °C
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储存方法
- -20°C for 12 months
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有效期
- 12 months
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- BVES (Blood Vessel Epicardial Substance (BVES))
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别名
- BVES
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背景
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Synonyms: Blood vessel epicardial substance (hBVES)|Popeye domain-containing protein 1 (Popeye protein 1)|BVES|POP1|POPDC1
Background: Cell adhesion molecule involved in the establishment and/or maintenance of cell integrity. Involved in the formation and regulation of the tight junction(TJ) paracellular permeability barrier in epithelial cells(PubMed:16188940). Plays a role in VAMP3-mediated vesicular transport and recycling of different receptor molecules through its interaction with VAMP3. Plays a role in the regulation of cell shape and movement by modulating the Rho-family GTPase activity through its interaction with ARHGEF25/GEFT. Induces primordial adhesive contact and aggregation of epithelial cells in a Ca(2+)-independent manner. Also involved in striated muscle regeneration and repair and in the regulation of cell spreading(By similarity). Important for the maintenance of cardiac function. Plays a regulatory function in heart rate dynamics mediated, at least in part, through cAMP-binding and, probably, by increasing cell surface expression of the potassium channel KCNK2 and enhancing current density(PubMed:26642364). Is also a caveolae-associated protein important for the preservation of caveolae structural and functional integrity as well as for heart protection against ischemia injury.
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分子量
- 41-70 kDa
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基因ID
- 11149
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UniProt
- Q8NE79
抗原
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