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Bestrophin 1 抗体 (AA 200-300)

This 兔 多克隆 anti-Bestrophin 1 antibody specifically detects Bestrophin 1 in WB, IHC 和 ELISA. The antibody is reactive with 人, 小鼠 和 大鼠 samples.
产品编号 ABIN7111981
发货至: 中国
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Quick Overview for Bestrophin 1 抗体 (AA 200-300) (ABIN7111981)

抗原

See all Bestrophin 1 (BEST1) 抗体
Bestrophin 1 (BEST1)

适用

  • 23
  • 4
  • 3
  • 2
  • 2
  • 1
人, 小鼠, 大鼠

宿主

  • 21
  • 4

克隆类型

  • 23
  • 2
多克隆

标记

  • 17
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
This Bestrophin 1 antibody is un-conjugated

应用范围

  • 18
  • 7
  • 5
  • 4
  • 3
  • 2
  • 1
  • 1
Western Blotting (WB), Immunohistochemistry (IHC), ELISA
  • 抗原表位

    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 200-300

    原理

    BEST1 antibody

    纯化方法

    Immunogen affinity purified

    纯度

    ≥95 % as determined by SDS-PAGE

    免疫原

    Immunogen sequence: 200-300aa

    Immunogen: bestrophin 1

    亚型

    IgG
  • 应用备注

    WB: 1:500 - 1:2000, IHC: 1:50 - 1:200

    限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

    PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    注意事项

    Avoid repeated freeze / thaw cycles.

    储存条件

    -20 °C

    储存方法

    -20°C for 12 months

    有效期

    12 months
  • 抗原

    Bestrophin 1 (BEST1)

    别名

    BEST1

    背景

    Synonyms: Bestrophin-1|TU15B|Vitelliform macular dystrophy protein 2|BEST1|VMD2

    Background: This gene encodes a member of the bestrophin gene family. This small gene family is characterized by proteins with a highly conserved N-terminus with four to six transmembrane domains. Bestrophins may form chloride ion channels or may regulate voltage-gated L-type calcium-ion channels. Bestrophins are generally believed to form calcium-activated chloride-ion channels in epithelial cells but they have also been shown to be highly permeable to bicarbonate ion transport in retinal tissue. Mutations in this gene are responsible for juvenile-onset vitelliform macular dystrophy (VMD2), also known as Best macular dystrophy, in addition to adult-onset vitelliform macular dystrophy (AVMD) and other retinopathies. Alternative splicing results in multiple variants encoding distinct isoforms.

    分子量

    70 kDa

    基因ID

    7439

    UniProt

    O76090
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