BCOR 抗体
Quick Overview for BCOR 抗体 (ABIN7111972)
抗原
See all BCOR 抗体适用
宿主
克隆类型
标记
应用范围
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原理
- BCOR antibody
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纯化方法
- Immunogen affinity purified
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纯度
- ≥95 % as determined by SDS-PAGE
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免疫原
- BCL6 co-repressor
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亚型
- IgG
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应用备注
- WB: 1:500 - 1:2000
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid repeated freeze / thaw cycles.
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储存条件
- -20 °C
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储存方法
- -20°C for 12 months
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有效期
- 12 months
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- BCOR (BCL6 Co-Repressor (BCOR))
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别名
- BCOR
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背景
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Synonyms: BCL-6 corepressor (BCoR)|BCOR|KIAA1575
Background: Transcriptional corepressor. May specifically inhibit gene expression when recruited to promoter regions by sequence-specific DNA-binding proteins such as BCL6 and MLLT3. This repression may be mediated at least in part by histone deacetylase activities which can associate with this corepressor. Involved in the repression of TFAP2A, impairs binding of BCL6 and KDM2B to TFAP2A promoter regions. Via repression of TFAP2A acts as a negative regulator of osteo-dentiogenic capacity in adult stem cells, the function implies inhibition of methylation on histone H3 'Lys-4'(H3K4me3) and 'Lys-36'(H3K36me2).
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分子量
- 186 kDa
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基因ID
- 54880
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UniProt
- Q6W2J9
抗原
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