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BHLHE22 抗体

BHLHE22 适用: 人, 小鼠 WB, ELISA, IF 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN7111942
发货至: 中国
  • 抗原 See all BHLHE22 抗体
    BHLHE22 (Basic Helix-Loop-Helix Family, Member E22 (BHLHE22))
    适用
    • 21
    • 5
    • 4
    • 4
    • 3
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    人, 小鼠
    宿主
    • 18
    • 2
    • 1
    克隆类型
    • 21
    多克隆
    标记
    • 11
    • 2
    • 2
    • 2
    • 2
    • 2
    This BHLHE22 antibody is un-conjugated
    应用范围
    • 21
    • 15
    • 12
    • 12
    • 1
    • 1
    • 1
    Western Blotting (WB), ELISA, Immunofluorescence (IF)
    纯化方法
    Immunogen affinity purified
    纯度
    ≥95 % as determined by SDS-PAGE
    免疫原
    basic helix-loop-helix family, member e22
    亚型
    IgG
    Top Product
    Discover our top product BHLHE22 Primary Antibody
  • 应用备注
    WB: 1:200-1:1000, IF: 1:10-1:100
    限制
    仅限研究用
  • 状态
    Liquid
    缓冲液
    PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    -20 °C
    储存方法
    -20°C for 12 months (Avoid repeated freeze / thaw cycles.)
    有效期
    12 months
  • 抗原
    BHLHE22 (Basic Helix-Loop-Helix Family, Member E22 (BHLHE22))
    别名
    BHLHE22 (BHLHE22 产品)
    别名
    bhlhb5 antibody, MGC145865 antibody, BHLHE22 antibody, Beta3.1 antibody, wu:fq25e11 antibody, zgc:64225 antibody, BHLHB5 antibody, Beta3 antibody, CAGL85 antibody, TNRC20 antibody, Bhlhb5 antibody, basic helix-loop-helix family member e22 antibody, basic helix-loop-helix family, member e22 antibody, bhlhe22 antibody, BHLHE22 antibody, Bhlhe22 antibody
    背景
    Synonyms:BHLHB5, TNRC20 Background:Inhibits DNA binding of TCF3/E47 homodimers and TCF3(E47)/NEUROD1 heterodimers and acts as a strong repressor of Neurod1 and Myod-responsive genes, probably by heterodimerization with class a basic helix-loop-helix factors. Despite the presence of an intact basic domain, does not bind to DNA(By similarity). In the brain, may function as an area-specific transcription factor that regulates the postmitotic acquisition of area identities and elucidate the genetic hierarchy between progenitors and postmitotic neurons driving neocortical arealization. May be required for the survival of a specific population of inhibitory neurons in the superficial laminae of the spinal chord dorsal horn that may regulate pruritis. Seems to play a crucial role in the retinogenesis, in the specification of amacrine and bipolar subtypes. Forms with PRDM8 a transcriptional repressor complex controlling genes involved in neural development and neuronal differentiation.
    分子量
    37 kDa
    基因ID
    27319
    UniProt
    Q8NFJ8
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