BHLHE22 抗体
Quick Overview for BHLHE22 抗体 (ABIN7111942)
抗原
See all BHLHE22 抗体适用
宿主
克隆类型
标记
应用范围
-
-
原理
- BHLHE22 antibody
-
纯化方法
- Immunogen affinity purified
-
纯度
- ≥95 % as determined by SDS-PAGE
-
免疫原
- basic helix-loop-helix family, member e22
-
亚型
- IgG
-
-
anti-Basic Helix-Loop-Helix Family, Member E22 (BHLHE22) (AA 236-264) antibody
BHLHE22 适用: 人 WB, FACS, IHC (p) 宿主: 兔 Polyclonal RB25879 unconjugated
anti-Basic Helix-Loop-Helix Family, Member E22 (BHLHE22) (AA 1-381) antibodyBHLHE22 适用: 人 WB 宿主: 小鼠 Polyclonal unconjugated
anti-Basic Helix-Loop-Helix Family, Member E22 (BHLHE22) (Internal Region) antibodyVerified BHLHE22 适用: 人 WB, ELISA 宿主: 山羊 Polyclonal unconjugated
anti-Basic Helix-Loop-Helix Family, Member E22 (BHLHE22) (AA 128-141) antibodyVerified BHLHE22 适用: 人 WB, ELISA 宿主: 山羊 Polyclonal unconjugated
anti-Basic Helix-Loop-Helix Family, Member E22 (BHLHE22) (AA 119-168) antibodyBHLHE22 适用: 人, 小鼠, 斑马鱼, Cow, 豚鼠, 兔, 小鸡, Pig, Hamster, 猴 WB 宿主: 兔 Polyclonal unconjugated
anti-Basic Helix-Loop-Helix Family, Member E22 (BHLHE22) (N-Term) antibodyBHLHE22 适用: 人, 小鼠, 大鼠, 斑马鱼, Cow, 豚鼠, 兔 WB 宿主: 兔 Polyclonal unconjugated
-
-
应用备注
- WB: 1:200-1:1000, IF: 1:10-1:100
-
限制
- 仅限研究用
-
-
-
状态
- Liquid
-
缓冲液
- PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,
-
储存液
- Sodium azide
-
注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
-
注意事项
- Avoid repeated freeze / thaw cycles.
-
储存条件
- -20 °C
-
储存方法
- -20°C for 12 months
-
有效期
- 12 months
-
-
- BHLHE22 (Basic Helix-Loop-Helix Family, Member E22 (BHLHE22))
-
别名
- BHLHE22
-
背景
-
Synonyms: Class E basic helix-loop-helix protein 22 (bHLHe22)|Class B basic helix-loop-helix protein 5 (bHLHb5)|Trinucleotide repeat-containing gene 20 protein|BHLHE22|BHLHB5|TNRC20
Background: Inhibits DNA binding of TCF3/E47 homodimers and TCF3(E47)/NEUROD1 heterodimers and acts as a strong repressor of Neurod1 and Myod-responsive genes, probably by heterodimerization with class a basic helix-loop-helix factors. Despite the presence of an intact basic domain, does not bind to DNA(By similarity). In the brain, may function as an area-specific transcription factor that regulates the postmitotic acquisition of area identities and elucidate the genetic hierarchy between progenitors and postmitotic neurons driving neocortical arealization. May be required for the survival of a specific population of inhibitory neurons in the superficial laminae of the spinal chord dorsal horn that may regulate pruritis. Seems to play a crucial role in the retinogenesis, in the specification of amacrine and bipolar subtypes. Forms with PRDM8 a transcriptional repressor complex controlling genes involved in neural development and neuronal differentiation.
-
分子量
- 37 kDa
-
基因ID
- 27319
-
UniProt
- Q8NFJ8
抗原
-
