CD79a 抗体
Quick Overview for CD79a 抗体 (ABIN7111904)
抗原
See all CD79a (CD79A) 抗体适用
宿主
克隆类型
标记
应用范围
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原理
- CD79A antibody
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纯化方法
- Immunogen affinity purified
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纯度
- ≥95 % as determined by SDS-PAGE
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免疫原
- CD79a molecule, immunoglobulin-associated alpha
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亚型
- IgG
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应用备注
- WB: 1:500-1:2000, IHC: 1:20-1:200
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid repeated freeze / thaw cycles.
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储存条件
- -20 °C
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储存方法
- -20°C for 12 months
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有效期
- 12 months
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- CD79a (CD79A) (B-cell antigen receptor complex-associated protein alpha chain (CD79A))
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别名
- CD79A
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背景
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Synonyms: B-cell antigen receptor complex-associated protein alpha chain|Ig-alpha|MB-1 membrane glycoprotein|Membrane-bound immunoglobulin-associated protein|Surface IgM-associated protein|CD79A|IGA|MB1
Background: Required in cooperation with CD79B for initiation of the signal transduction cascade activated by binding of antigen to the B-cell antigen receptor complex(BCR) which leads to internalization of the complex, trafficking to late endosomes and antigen presentation. Also required for BCR surface expression and for efficient differentiation of pro-and pre-B-cells. Stimulates SYK autophosphorylation and activation. Binds to BLNK, bringing BLNK into proximity with SYK and allowing SYK to phosphorylate BLNK. Also interacts with and increases activity of some Src-family tyrosine kinases. Represses BCR signaling during development of immature B-cells.
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分子量
- 40 kDa
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UniProt
- P11912
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途径
- BCR Signaling
抗原
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