ABCC6 抗体
Quick Overview for ABCC6 抗体 (ABIN7111820)
抗原
See all ABCC6 抗体适用
宿主
克隆类型
标记
应用范围
-
-
原理
- ABCC6 antibody
-
纯化方法
- Immunogen affinity purified
-
纯度
- ≥95 % as determined by SDS-PAGE
-
免疫原
-
Immunogen sequence: 1437-1499
Immunogen: ATP-binding cassette, sub-family C (CFTR/MRP), member 6
-
亚型
- IgG
-
-
-
-
应用备注
- IHC: 1:20-1:200
-
限制
- 仅限研究用
-
-
-
状态
- Liquid
-
缓冲液
- PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,
-
储存液
- Sodium azide
-
注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
-
注意事项
- Avoid repeated freeze / thaw cycles.
-
储存条件
- -20 °C
-
储存方法
- -20°C for 12 months
-
有效期
- 12 months
-
-
- ABCC6 (ATP-Binding Cassette, Sub-Family C (CFTR/MRP), Member 6 (ABCC6))
-
别名
- ABCC6
-
背景
-
Synonyms: ATP-binding cassette sub-family C member 6|Anthracycline resistance-associated protein|Multi-specific organic anion transporter E (MOAT-E)|Multidrug resistance-associated protein 6|ABCC6|ARA|MRP6
Background: The ATP-binding cassette transporter 6 (ABCC6) gene, also named as MRP6, is a cellular transmembrane protein transporter and belongs to ATP-binding cassette (ABC) family. ABCC6 is an ATP-dependent transporter contains two ATP-binding domains. It is mainly found in the liver, the proximal tubules of the kidneys and the intestines. ABCC6 is involved in a pathway of extracellular nucleotide metabolism and the regulation of tissue calcification. Mutations of ABCC6 leads to pseudoxanthoma elasticum (PXE) which is a rare autosomal recessive disorder. Mutations of ABCC6 can also lead generalized arterial calcification of infancy-2 (GACI2).
-
分子量
- 165 kDa
-
UniProt
- O95255
抗原
-