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Liver Arginase 抗体 (AA 1-236)

The 小鼠 单克隆 anti-Liver Arginase antibody (Clone 4A0) (ABIN7111710) specifically detects Liver Arginase in WB, IHC, ELISA 和 IF. The antibody is reactive with 人, 大鼠 和 小鼠 samples.
产品编号 ABIN7111710
发货至: 中国
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Quick Overview for Liver Arginase 抗体 (AA 1-236) (ABIN7111710)

抗原

See all Liver Arginase (ARG1) 抗体
Liver Arginase (ARG1) (Arginase, Liver (ARG1))

适用

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人, 大鼠, 小鼠

宿主

  • 134
  • 40
  • 5
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  • 1
小鼠

克隆类型

  • 109
  • 75
  • 1
单克隆

标记

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This Liver Arginase antibody is un-conjugated

应用范围

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Western Blotting (WB), Immunohistochemistry (IHC), ELISA, Immunofluorescence (IF)

克隆位点

4A0
  • 抗原表位

    • 24
    • 16
    • 12
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    • 7
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    AA 1-236

    原理

    ARG1 antibody

    纯化方法

    Protein A+G purification

    纯度

    ≥95 % as determined by SDS-PAGE

    免疫原

    Immunogen sequence: 1-236aa

    Immunogen: arginase, liver

    亚型

    IgG2a
  • 应用备注

    WB: 1:1000-1:8000, IHC: 1:200-1:1000, IF:1:50-1:200

    限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

    PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    注意事项

    Avoid repeated freeze / thaw cycles.

    储存条件

    -20 °C

    储存方法

    -20°C for 12 months

    有效期

    12 months
  • 抗原

    Liver Arginase (ARG1) (Arginase, Liver (ARG1))

    别名

    ARG1

    背景

    Synonyms: Arginase-1|Liver-type arginase|Type I arginase|ARG1

    Background: Arginase-1(Liver arginase) belongs to the arginase family. ARG1 is a novel immunohistochemicalmarkerof hepatocellular differentiation in fine needle aspiration cytology and a markerof hepatocytes and hepatocellular neoplasms. ARG1 is closely associated with alternative macrophage activation(PMID:12098359) and ARG1 has been shown to protectmotor neurons from trophic factor deprivation and allow sensory neurons to overcome neurite outgrowth inhibition by myelin proteins(PMID: 20071539).It can exsit as a homotrimer(PMID:16141327) and it has 3 isoforms produced by alternative splicing.Defects in ARG1 are the cause of argininemia(ARGIN). Deletion or TNF-mediated restriction of ARG1 unleashes the production of NO by NOS2, which is critical for pathogen control.(PMID:27117406).

    分子量

    35 kDa

    基因ID

    383

    UniProt

    P05089

    途径

    Cellular Response to Molecule of Bacterial Origin
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