Liver Arginase 抗体
Quick Overview for Liver Arginase 抗体 (ABIN7111709)
抗原
See all Liver Arginase (ARG1) 抗体适用
宿主
克隆类型
标记
应用范围
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纯化方法
- Immunogen affinity purified
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纯度
- ≥95 % as determined by SDS-PAGE
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免疫原
- arginase, liver
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亚型
- IgG
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应用备注
- WB: 1:1000-1:10000, IP: 1:500-1:1000, IHC: 1:100-1:400, IF: 1:20-1:200
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- -20°C for 12 months (Avoid repeated freeze / thaw cycles.)
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有效期
- 12 months
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- Liver Arginase (ARG1) (Arginase, Liver (ARG1))
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别名
- liver Arginase
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背景
- Synonyms:ARG1, Arginase 1, liver Arginase, Liver type arginase Background:Arginase-1(Liver arginase) belongs to the arginase family. ARG1 is a novel immunohistochemicalmarkerof hepatocellular differentiation in fine needle aspiration cytology and a markerof hepatocytes and hepatocellular neoplasms. ARG1 is closely associated with alternative macrophage activation(PMID:12098359) and ARG1 has been shown to protectmotor neurons from trophic factor deprivation and allow sensory neurons to overcome neurite outgrowth inhibition by myelin proteins(PMID: 20071539).It can exsit as a homotrimer(PMID:16141327) and it has 3 isoforms produced by alternative splicing.Defects in ARG1 are the cause of argininemia(ARGIN). Deletion or TNF-mediated restriction of ARG1 unleashes the production of NO by NOS2, which is critical for pathogen control.(PMID:27117406).
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分子量
- 35 kDa
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基因ID
- 383
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UniProt
- P05089
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途径
- Cellular Response to Molecule of Bacterial Origin
抗原
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