ANKRD15 抗体
Quick Overview for ANKRD15 抗体 (ABIN7111596)
抗原
See all ANKRD15 抗体适用
宿主
克隆类型
标记
应用范围
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原理
- KANK1 antibody
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纯化方法
- Immunogen affinity purified
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纯度
- ≥95 % as determined by SDS-PAGE
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免疫原
- KN motif and ankyrin repeat domains 1
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亚型
- IgG
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anti-Ankyrin Repeat Domain 15 (ANKRD15) antibody
ANKRD15 适用: 人 WB, IHC (p) 宿主: 小鼠 Monoclonal 1773CT634-49-61 unconjugated
anti-Ankyrin Repeat Domain 15 (ANKRD15) (AA 701-800) antibodyANKRD15 适用: 人 WB, ELISA 宿主: 小鼠 Monoclonal 2B8 unconjugated
anti-Ankyrin Repeat Domain 15 (ANKRD15) (AA 66-255) antibodyANKRD15 适用: 人 ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Ankyrin Repeat Domain 15 (ANKRD15) (AA 900-1000) antibodyANKRD15 适用: 人 WB, IF 宿主: 兔 Polyclonal unconjugated
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应用备注
- WB: 1:500-1:2000, IHC: 1:20-1:200, IF: 1:20-1:200
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid repeated freeze / thaw cycles.
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储存条件
- -20 °C
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储存方法
- -20°C for 12 months
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有效期
- 12 months
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- ANKRD15 (Ankyrin Repeat Domain 15 (ANKRD15))
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别名
- KANK1
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背景
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Synonyms: KN motif and ankyrin repeat domain-containing protein 1|Ankyrin repeat domain-containing protein 15|Kidney ankyrin repeat-containing protein|KANK1|ANKRD15|KANK|KIAA0172
Background: Involved in the control of cytoskeleton formation by regulating actin polymerization. Inhibits actin fiber formation and cell migration. Inhibits RhoA activity, the function involves phosphorylation through PI3K/Akt signaling and may depend on the competetive interaction with 14-3-3 adapter proteins to sequester them from active complexes. Inhibits the formation of lamellipodia but not of filopodia, the function may depend on the competetive interaction with BAIAP2 to block its association with activated RAC1. Inhibits fibronectin-mediated cell spreading, the function is partially mediated by BAIAP2. Inhibits neurite outgrowth. Involved in the establishment and persistence of cell polarity during directed cell movement in wound healing. In the nucleus, is involved in beta-catenin-dependent activation of transcription. Potential tumor suppressor for renal cell carcinoma.
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分子量
- 150 kDa
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基因ID
- 23189
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UniProt
- Q14678
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途径
- Regulation of Actin Filament Polymerization
抗原
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