ANGPTL4 抗体
Quick Overview for ANGPTL4 抗体 (ABIN7111567)
抗原
See all ANGPTL4 抗体适用
宿主
克隆类型
标记
应用范围
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原理
- ANGPTL4 antibody
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纯化方法
- Immunogen affinity purified
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纯度
- ≥95 % as determined by SDS-PAGE
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免疫原
- angiopoietin-like 4
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亚型
- IgG
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应用备注
- WB: 1:200-1:2000, IHC: 1:20-1:200, IF: 1:20-1:200, IP: 1:200-1:2000
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid repeated freeze / thaw cycles.
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储存条件
- -20 °C
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储存方法
- -20°C for 12 months
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有效期
- 12 months
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- ANGPTL4 (Angiopoietin-Like 4 (ANGPTL4))
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别名
- ANGPTL4
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背景
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Synonyms: Angiopoietin-related protein 4|Angiopoietin-like protein 4|Hepatic fibrinogen/angiopoietin-related protein (HFARP)|ANGPTL4 N-terminal chain|ANGPTL4 C-terminal chain|ANGPTL4|ARP4|HFARP|PGAR
Background: Protein with hypoxia-induced expression in endothelial cells. May act as a regulator of angiogenesis and modulate tumorigenesis. Inhibits proliferation, migration, and tubule formation of endothelial cells and reduces vascular leakage. May exert a protective function on endothelial cells through an endocrine action. It is directly involved in regulating glucose homeostasis, lipid metabolism, and insulin sensitivity. In response to hypoxia, the unprocessed form of the protein accumulates in the subendothelial extracellular matrix(ECM). The matrix-associated and immobilized unprocessed form limits the formation of actin stress fibers and focal contacts in the adhering endothelial cells and inhibits their adhesion. It also decreases motility of endothelial cells and inhibits the sprouting and tube formation(By similarity).
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分子量
- 45 kDa
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基因ID
- 51129
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UniProt
- Q9BY76
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途径
- Regulation of Lipid Metabolism by PPARalpha
抗原
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