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Aminoacylase 1 抗体

This anti-Aminoacylase 1 antibody is a 兔 多克隆 antibody detecting Aminoacylase 1 in WB, IHC, ELISA 和 IF. Suitable for 人, 小鼠 和 大鼠.
产品编号 ABIN7111519
发货至: 中国

Quick Overview for Aminoacylase 1 抗体 (ABIN7111519)

抗原

See all Aminoacylase 1 (ACY1) 抗体
Aminoacylase 1 (ACY1)

适用

  • 34
  • 13
  • 3
  • 2
  • 1
  • 1
人, 小鼠, 大鼠

宿主

  • 21
  • 14
  • 2

克隆类型

  • 23
  • 14
多克隆

标记

  • 30
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
This Aminoacylase 1 antibody is un-conjugated

应用范围

  • 28
  • 15
  • 12
  • 7
  • 7
  • 6
  • 6
  • 4
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
Western Blotting (WB), Immunohistochemistry (IHC), ELISA, Immunofluorescence (IF)
  • 纯化方法

    Immunogen affinity purified

    纯度

    ≥95 % as determined by SDS-PAGE

    免疫原

    aminoacylase 1

    亚型

    IgG
  • 应用备注

    WB: 1:500 - 1:2000, IHC: 1:50 - 1:200, IF: 1:50 - 1:200

    限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

    PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3 ,

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    -20°C for 12 months (Avoid repeated freeze / thaw cycles.)

    有效期

    12 months
  • 抗原

    Aminoacylase 1 (ACY1)

    别名

    Aminoacylase 1

    背景

    Synonyms:ACY 1, ACY1, ACY1D, ACYLASE, Aminoacylase 1 Background:This gene encodes a cytosolic, homodimeric, zinc-binding enzyme that catalyzes the hydrolysis of acylated L-amino acids to L-amino acids and an acyl group, and has been postulated to function in the catabolism and salvage of acylated amino acids. This gene is located on chromosome 3p21.1, a region reduced to homozygosity in small-cell lung cancer (SCLC), and its expression has been reported to be reduced or undetectable in SCLC cell lines and tumors. The amino acid sequence of human aminoacylase-1 is highly homologous to the porcine counterpart, and this enzyme is the first member of a new family of zinc-binding enzymes. Mutations in this gene cause aminoacylase-1 deficiency, a metabolic disorder characterized by central nervous system defects and increased urinary excretion of N-acetylated amino acids. Alternative splicing of this gene results in multiple transcript variants. Read-through transcription also exists between this gene and the upstream ABHD14A (abhydrolase domain containing 14A) gene, as represented in GeneID:100526760. A related pseudogene has been identified on chromosome 18.

    分子量

    46 kDa

    基因ID

    95

    UniProt

    Q03154
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