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alpha KGDHC 抗体

This anti-alpha KGDHC antibody is a 兔 多克隆 antibody detecting alpha KGDHC in WB, IHC, ELISA 和 IF. Suitable for 人, 大鼠 和 小鼠.
产品编号 ABIN7111489
发货至: 中国

Quick Overview for alpha KGDHC 抗体 (ABIN7111489)

抗原

See all alpha KGDHC (alphaKGDHC) 抗体
alpha KGDHC (alphaKGDHC) (alpha Ketoglutarate Dehydrogenase (alphaKGDHC))

适用

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人, 大鼠, 小鼠

宿主

  • 28
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克隆类型

  • 28
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多克隆

标记

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This alpha KGDHC antibody is un-conjugated

应用范围

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Western Blotting (WB), Immunohistochemistry (IHC), ELISA, Immunofluorescence (IF)
  • 原理

    OGDH antibody

    纯化方法

    Immunogen affinity purified

    纯度

    ≥95 % as determined by SDS-PAGE

    免疫原

    oxoglutarate (alpha-ketoglutarate) dehydrogenase (lipoamide)

    亚型

    IgG
  • 应用备注

    WB: 1:500 - 1:2000, IHC: 1:50 - 1:200, IF: 1:50 - 1:100

    限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

    PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    注意事项

    Avoid repeated freeze / thaw cycles.

    储存条件

    -20 °C

    储存方法

    -20°C for 12 months

    有效期

    12 months
  • 抗原

    alpha KGDHC (alphaKGDHC) (alpha Ketoglutarate Dehydrogenase (alphaKGDHC))

    别名

    OGDH

    背景

    Synonyms: 2-oxoglutarate dehydrogenase complex component E1 (E1o, OGDC-E1, OGDH-E1)|2-oxoglutarate dehydrogenase, mitochondrial|Alpha-ketoglutarate dehydrogenase (Alpha-KGDH-E1)|Thiamine diphosphate (ThDP)-dependent 2-oxoglutarate dehydrogenase|OGDH

    Background: This gene encodes one subunit of the 2-oxoglutarate dehydrogenase complex. This complex catalyzes the overall conversion of 2-oxoglutarate (alpha-ketoglutarate) to succinyl-CoA and CO(2) during the Krebs cycle. The protein is located in the mitochondrial matrix and uses thiamine pyrophosphate as a cofactor. A congenital deficiency in 2-oxoglutarate dehydrogenase activity is believed to lead to hypotonia, metabolic acidosis, and hyperlactatemia. Alternative splicing results in multiple transcript variants encoding distinct isoforms.

    分子量

    116 kDa

    基因ID

    4967

    UniProt

    Q02218
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