ALKBH5 抗体
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北京 101111
Quick Overview for ALKBH5 抗体 (ABIN7111483)
抗原
See all ALKBH5 抗体适用
宿主
克隆类型
标记
应用范围
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原理
- ALKBH5 antibody
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纯化方法
- Immunogen affinity purified
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纯度
- ≥95 % as determined by SDS-PAGE
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免疫原
- alkB, alkylation repair homolog 5(E. coli)
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亚型
- IgG
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anti-AlkB, Alkylation Repair Homolog 5 (ALKBH5) (AA 245-394) antibody
ALKBH5 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
anti-AlkB, Alkylation Repair Homolog 5 (ALKBH5) (AA 302-330) antibodyALKBH5 适用: 人 WB, IHC (p), FACS 宿主: 兔 Polyclonal RB38474 unconjugated
anti-AlkB, Alkylation Repair Homolog 5 (ALKBH5) (AA 1-458) antibodyALKBH5 适用: 人 WB 宿主: 小鼠 Polyclonal unconjugated
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应用备注
- WB: 1:200-1:2000, IHC: 1:20-1:200
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid repeated freeze / thaw cycles.
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储存条件
- -20 °C
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储存方法
- -20°C for 12 months
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有效期
- 12 months
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- ALKBH5 (AlkB, Alkylation Repair Homolog 5 (ALKBH5))
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别名
- ALKBH5
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背景
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Synonyms: RNA demethylase ALKBH5|Alkylated DNA repair protein alkB homolog 5|Alpha-ketoglutarate-dependent dioxygenase alkB homolog 5|ALKBH5|ABH5|OFOXD1
Background: Dioxygenase that demethylates RNA by oxidative demethylation: specifically demethylates N(6)-methyladenosine(m6A) RNA, the most prevalent internal modification of messenger RNA(mRNA) in higher eukaryotes(PubMed:23177736, PubMed:24778178, PubMed:24616105, PubMed:24489119). Can also demethylate N(6)-methyladenosine in single-stranded DNA(in vitro)(PubMed:24616105). Requires molecular oxygen, alpha-ketoglutarate and iron(PubMed:21264265, PubMed:23177736, PubMed:24778178, PubMed:24616105, PubMed:24489119). Demethylation of m6A mRNA affects mRNA processing and export(PubMed:23177736). Required for spermatogenesis(By similarity).
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分子量
- 51 kDa
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基因ID
- 54890
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UniProt
- Q6P6C2
抗原
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