AFF4 抗体 (AA 1-307)
Quick Overview for AFF4 抗体 (AA 1-307) (ABIN7111407)
抗原
See all AFF4 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 1-307
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原理
- AFF4 antibody
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纯化方法
- Immunogen affinity purified
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纯度
- ≥95 % as determined by SDS-PAGE
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免疫原
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Immunogen sequence: 1-307aa
Immunogen: AF4/FMR2 family, member 4
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亚型
- IgG
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应用备注
- WB: 1:200-1:2000
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid repeated freeze / thaw cycles.
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储存条件
- -20 °C
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储存方法
- -20°C for 12 months
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有效期
- 12 months
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- AFF4 (AF4/FMR2 Family, Member 4 (AFF4))
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别名
- AFF4
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背景
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Synonyms: AF4/FMR2 family member 4|ALL1-fused gene from chromosome 5q31 protein (Protein AF-5q31)|Major CDK9 elongation factor-associated protein|AFF4|AF5Q31|MCEF
Background: Key component of the super elongation complex(SEC), a complex required to increase the catalytic rate of RNA polymerase II transcription by suppressing transient pausing by the polymerase at multiple sites along the DNA. In the SEC complex, AFF4 acts as a central scaffold that recruits other factors through direct interactions with ELL proteins(ELL, ELL2 or ELL3) and the P-TEFb complex. In case of infection by HIV-1 virus, the SEC complex is recruited by the viral Tat protein to stimulate viral gene expression.
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分子量
- 150 kDa
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基因ID
- 27125
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UniProt
- Q9UHB7
抗原
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