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ARL2 抗体

This anti-ARL2 antibody is a 兔 多克隆 antibody detecting ARL2 in WB, ELISA 和 IHC. Suitable for 人, 小鼠 和 大鼠.
产品编号 ABIN7111380
发货至: 中国

Quick Overview for ARL2 抗体 (ABIN7111380)

抗原

See all ARL2 抗体
ARL2 (ADP-Ribosylation Factor-Like 2 (ARL2))

适用

人, 小鼠, 大鼠

宿主

  • 44
  • 1
  • 1

克隆类型

  • 46
多克隆

标记

  • 21
  • 5
  • 4
  • 3
  • 3
  • 3
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
This ARL2 antibody is un-conjugated

应用范围

  • 30
  • 23
  • 16
  • 10
  • 5
  • 4
  • 3
  • 2
  • 2
Western Blotting (WB), ELISA, Immunohistochemistry (IHC)
  • 纯化方法

    Immunogen affinity purified

    纯度

    ≥95 % as determined by SDS-PAGE

    免疫原

    ADP-ribosylation factor-like 2

    亚型

    IgG
  • 应用备注

    WB: 1:500-1:2000, IHC: 1:20-1:200

    限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

    PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    -20°C for 12 months (Avoid repeated freeze / thaw cycles.)

    有效期

    12 months
  • 抗原

    ARL2 (ADP-Ribosylation Factor-Like 2 (ARL2))

    别名

    ARL2

    背景

    Synonyms: Background:Small GTP-binding protein which cycles between an inactive GDP-bound and an active GTP-bound form, and the rate of cycling is regulated by guanine nucleotide exchange factors(GEF) and GTPase-activating proteins(GAP). GTP-binding protein that does not act as an allosteric activator of the cholera toxin catalytic subunit. Regulates formation of new microtubules and centrosome integrity. Prevents the TBCD-induced microtubule destruction. Participates in association with TBCD, in the disassembly of the apical junction complexes. Antagonizes the effect of TBCD on epithelial cell detachment and tight and adherens junctions disassembly. Together with ARL2, plays a role in the nuclear translocation, retention and transcriptional activity of STAT3. Component of a regulated secretory pathway involved in Ca(2+)-dependent release of acetylcholine. Required for normal progress through the cell cycle.

    分子量

    21-25 kDa

    基因ID

    402

    UniProt

    P36404

    途径

    Cell-Cell Junction Organization, Maintenance of Protein Location
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